Z-VAD-FMK (Highly Pure)

Description

Z-VAD-FMK
Catalog number: B2014303
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 2 mg
Molecular Weight or Concentration: 467.49 g/mol
Supplied as: Solid
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: Z-VAD-FMK
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Pagano N, Longobardi V, De Canditiis C, Zuchegna C, Romano A, Michal Andrzej K, Pero ME, Gasparrini B. Effect of caspase inhibitor Z-VAD-FMK on bovine sperm cryotolerance Reprod Domest Anim. 2020 Apr;55(4):530-536.
2: Costa Pereira LM, Thongkittidilok C, Lopes MD, Songsasen N. Effect of anti-apoptotic drug Z-VAD-FMK on invitro viability of dog follicles Theriogenology. 2018 Dec;122:124-129.
3: Chang H, Sun F, Tian K, Wang W, Zhou K, Zha D, Qiu J. Caspase inhibitor z-VAD-FMK increases the survival of hair cells after Actinomycin-D-induced damage in vitro Neurosci Lett. 2020 Jul 27;732:135089.
4: Van Noorden CJ. The history of Z-VAD-FMK, a tool for understanding the significance of caspase inhibition Acta Histochem. 2001 Jul;103(3):241-51.
5: Martinet W, Schrijvers DM, Herman AG, De Meyer GR. z-VAD-fmk-induced non-apoptotic cell death of macrophages: possibilities and limitations for atherosclerotic plaque stabilization Autophagy. 2006 Oct-Dec;2(4):312-4.
6: Fransolet M, Nol L, Henry L, Labied S, Blacher S, Nisolle M, Munaut C. Evaluation of Z-VAD-FMK as an anti-apoptotic drug to prevent granulosa cell apoptosis and follicular death after human ovarian tissue transplantation J Assist Reprod Genet. 2019 Feb;36(2):349-359.
7: Yu C, Lei Z, Li X, Huang LH, Li ZQ, Zhu HW, Han D, Huang H, Yu X. Role of HMGB1 in TNF- Combined with Z_VAD-fmk-Induced L929 Cells Necroptosis Biochem Genet. 2022 Apr;60(2):598-610.
8: Cowburn AS, White JF, Deighton J, Walmsley SR, Chilvers ER. z-VAD-fmk augmentation of TNF alpha-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species Blood. 2005 Apr 1;105(7):2970-2.
9: He M, Zhang G, Shen F, Li X. Effects of Z_VaD-Ala-Asp-Fluoromethyl Ketone (Z_VAD-FMK) and Acetyl-Asp-Glu-Val-Asp-Aldehyde(Ac-DEVD-CHO) on Inflammation and Mucus Secretion in Mice Exposed to Cigarette Smoke Int J Chron Obstruct Pulmon Dis. 2023 Feb 5;18:69-78.
10: Pero ME, Zullo G, Esposito L, Iannuzzi A, Lombardi P, De Canditiis C, Neglia G, Gasparrini B. Inhibition of apoptosis by caspase inhibitor Z-VAD-FMK improves cryotolerance of invitro derived bovine embryos Theriogenology. 2018 Mar 1;108:127-135.

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