Z-Phe-Ala Fluoromethyl Ketone


Catalog Number: B2013754 (3 mg)
Z-Phe-Ala Fluoromethyl Ketone is a high quality Z-Phe-Ala fluoromethyl ketone. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Z-Phe-Ala Fluoromethyl Ketone
Catalog number: B2013754
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 3 mg
Molecular Weight or Concentration: 386.42 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Z-FA-FMK
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Eichhold TH, Hookfin EB, Taiwo YO, De B, Wehmeyer KR. Isolation and quantification of fluoroacetate in rat tissues, following dosing of Z-Phe-Ala-CH2-F, a peptidyl fluoromethyl ketone protease inhibitor J Pharm Biomed Anal. 1997 Nov;16(3):459-67.
2: Richer JK, Hunt WG, Sakanari JA, Grieve RB. Dirofilaria immitis: effect of fluoromethyl ketone cysteine protease inhibitors on the third- to fourth-stage molt Exp Parasitol. 1993 May;76(3):221-31.
3: Gulyaeva NV, Kudryashov IE, Kudryashova IV. Caspase activity is essential for long-term potentiation J Neurosci Res. 2003 Sep 15;73(6):853-64.
4: Kelsall BL, Ravdin JI. Degradation of human IgA by Entamoeba histolytica J Infect Dis. 1993 Nov;168(5):1319-22.
5: Sheen-Chen SM, Ho HT, Chen WJ, Eng HL. Effect of ZVAD-fmk on hepatocyte apoptosis after bile duct ligation in rat World J Gastroenterol. 2005 Apr 21;11(15):2330-3.
6: Gottron FJ, Ying HS, Choi DW. Caspase inhibition selectively reduces the apoptotic component of oxygen-glucose deprivation-induced cortical neuronal cell death Mol Cell Neurosci. 1997;9(3):159-69.
7: Eakin AE, McGrath ME, McKerrow JH, Fletterick RJ, Craik CS. Production of crystallizable cruzain, the major cysteine protease from Trypanosoma cruzi J Biol Chem. 1993 Mar 25;268(9):6115-8.
8: Guo H, Tittle TV, Allen H, Maziarz RT. Brefeldin A-mediated apoptosis requires the activation of caspases and is inhibited by Bcl-2 Exp Cell Res. 1998 Nov 25;245(1):57-68.
9: Jord EG, Verdaguer E, Jimenez A, Arriba SG, Allgaier C, Palls M, Camins A. Evaluation of the neuronal apoptotic pathways involved in cytoskeletal disruption-induced apoptosis Biochem Pharmacol. 2005 Aug 1;70(3):470-80.
10: Aldape K, Huizinga H, Bouvier J, McKerrow J. Naegleria fowleri: characterization of a secreted histolytic cysteine protease Exp Parasitol. 1994 Mar;78(2):230-41.

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Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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