[Tyr8]-Substance P

Product Description

[Tyr8]-Substance P
Catalog number: MDP0409
CAS Number: 95602-96-3
Sequence: Arg-Pro-Lys-Pro-Gln-Gln-Phe-Tyr-Gly-Leu-Met-NH2
Amount: 500 ug
Molecular Weight: 1363.6 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20 °C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.

References:
1: Rissler K, Cramer H, Engelmann P. Application of [(125)I]-[Tyr8]-substance P prepared by the chloramine-T method to receptor-binding experiments after subsequent reduction with mercaptoethanol and purification by reversed-phase liquid chromatography J Chromatogr B Biomed Sci Appl. 1997 Sep 26;698(1-2):17-26.
2: Rissler K, Cramer H. Marked improvement of a substance P radioimmunoassay by reduction of 125I-labelled [Tyr8]-substance P prepared by the chloramine-T method with mercaptoethanol and subsequent purification by reversed-phase liquid chromatography J Chromatogr. 1991 Mar 8;564(1):67-79.
3: Higa K, Gao C, Motokawa W, Abe K. Sialogogic activity in the rat of peptides analogous to [Tyr8]-substance P in which substitutions have been made in the N-terminal amino acids Arch Oral Biol. 2001 Apr;46(4):313-21.
4: Malencik DA, Anderson SR. Peptide cross-linking to calmodulin: attachment of [Tyr8]substance P Biochemistry. 1988 Feb 9;27(3):944-50.
5: Saria A, Mayer N, Lembeck F, Pabst M. Regional distribution and biochemical properties of 125I-Tyr8-substance P binding sites in synaptic vesicles Naunyn Schmiedebergs Arch Pharmacol. 1980 Mar;311(2):151-7.
6: Fisher GH, Folkers K, Pernow B, Bowers CY. Synthesis and some biological activities of the tyrosine-8 analog of substance P J Med Chem. 1976 Feb;19(2):325-8.
7: Beaujouan JC, Torrens Y, Herbet A, Daguet MC, Glowinski J, Prochiantz A. Specific binding of an immunoreactive and biologically active 125I-labeled substance P derivative to mouse mesencephalic cells in primary culture Mol Pharmacol. 1982 Jul;22(1):48-55.
8: Convert O, Ploux O, Lavielle S, Cotrait M, Chassaing G. Analysis of tachykinin-binding site interactions using NMR and energy calculation data of potent cyclic analogues of substance P Biochim Biophys Acta. 1988 Jun 13;954(3):287-302.
9: Cierniewski CS, Babińska A, Koziołkiewicz W, Wasiak T. Immunochemical analysis of substance P using its synthetic fragments and analogs Hoppe Seylers Z Physiol Chem. 1984 Apr;365(4):499-502.
10: McKee KT, Millar L, Rodger IW, Metters KM. Identification of both NK1 and NK2 receptors in guinea-pig airways Br J Pharmacol. 1993 Oct;110(2):693-700.

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