[Tyr34]-Parathyroid Hormone (Bovine, 1-34 Amide)

Product Description

[Tyr34]-Parathyroid Hormone (Bovine, 1-34 Amide)
Catalog number: MDP0564
CAS Number: N/A
Sequence: Ala-Val-Ser-Glu-Ile-Gln-Phe-Met-His-Asn-Leu-Gly-Lys-His-Leu-Ser-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Tyr-NH2
Amount: 500 ug
Molecular Weight: 4123.6 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20 °C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.

References:
1: Pizurki L, Rizzoli R, Bonjour JP. Inhibition by (D-Trp12,Tyr34)bPTH(7-34)amide of PTH and PTHrP effects on Pi transport in renal cells Am J Physiol. 1990 Aug;259(2 Pt 2):F389-92.
2: Dresner-Pollak R, Yang QM, Behar V, Nakamoto C, Chorev M, Rosenblatt M. Evaluation in vivo of a potent parathyroid hormone antagonist: [Nle8,18,D-Trp12,Tyr34]bPTH(7-34)NH2 J Bone Miner Res. 1996 Aug;11(8):1061-5.
3: Goldman ME, McKee RL, Caulfield MP, Reagan JE, Levy JJ, Gay CT, DeHaven PA, Rosenblatt M, Chorev M. A new highly potent parathyroid hormone antagonist: [D-Trp12,Tyr34]bPTH-(7-34)NH2 Endocrinology. 1988 Nov;123(5):2597-9.
4: Singh AT, Kunnel JG, Strieleman PJ, Stern PH. Parathyroid hormone (PTH)-(1-34), [Nle(8,18),Tyr34]PTH-(3-34) amide, PTH-(1-31) amide, and PTH-related peptide-(1-34) stimulate phosphatidylcholine hydrolysis in UMR-106 osteoblastic cells: comparison with effects of phorbol 12,13-dibutyrate Endocrinology. 1999 Jan;140(1):131-7.
5: Shew RL, Robinson MF, Olansky L, Yee JA. Inhibitory effect of [Tyr34]bPTH-(7-34)-amide on bPTH-(1-34) ability to reduce uterine contraction Pharmacology. 1989;39(6):390-6.
6: Laverty G, Alberici M, Gorman AN. Effects of the parathyroid hormone antagonist [Tyr34]bPTH-(7-34)amide on avian renal phosphate transport Gen Comp Endocrinol. 1988 Feb;69(2):281-7.
7: Hlavica P, Kellermann J, Golly I, Lehnerer M. Chemical modification of Tyr34 and Tyr129 in rabbit liver microsomal cytochrome b5 affects interaction with cytochrome P-450 2B4 Eur J Biochem. 1994 Sep 15;224(3):1039-46.
8: Shigeno C, Hiraki Y, Keutmann HT, Stern AM, Potts JT Jr, Segre GV. Preparation of a photoreactive analog of parathyroid hormone [Nle8, Lys(N-epsilon-4-azido-2-nitrophenyl)13,Nle18,Tyr34]bovine parathyroid hormone-(1-34)NH2, a selective, high-affinity ligand for characterization of parathyroid hormone receptors Anal Biochem. 1989 Jun;179(2):268-73.
9: Jüppner H. Functional properties of the PTH/PTHrP receptor Bone. 1995 Aug;17(2 Suppl):39S-42S.
10: Mateluna C, Torres P, Rodriguez-Peña M, Silva P, Matthies DJ, Criollo A, Bikker FJ, Bolscher JGM, Wilson CAM, Zapata-Torres G, Torres VA. Identification of VEGFR2 as the Histatin-1 receptor in endothelial cells Biochem Pharmacol. 2022 Jul;201:115079.

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