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Tissue Plasminogen Activator Chromogenic Substrate

$895.00

Catalog Number: B2012537 (5 mg)
Tissue Plasminogen Activator Chromogenic Substrate is a high quality highly sensitive chromogenic peptide substrate for tissue plasminogen activator (tPA). This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2012537 Categories: , Tag:

Description

Tissue Plasminogen Activator Chromogenic Substrate
Catalog number: B2012537
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 658.9 g/mol
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: PA, tPA
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Matsuo O, Sakai T, Takakura Y, Mihara H. Substrate specificity of tissue plasminogen activator and urokinase as determined with synthetic chromogenic substrates Jpn J Physiol. 1983;33(6):1031-7.
2: Gleeson NC. Cyclic changes in endometrial tissue plasminogen activator and plasminogen activator inhibitor type 1 in women with normal menstruation and essential menorrhagia Am J Obstet Gynecol. 1994 Jul;171(1):178-83.
3: Liang JF, Li Y, Yang VC. The potential mechanism for the effect of heparin on tissue plasminogen activator-mediated plasminogen activation Thromb Res. 2000 Mar 1;97(5):349-58.
4: Okada K, Ueshima S, Matsuno H, Nagai N, Kawao N, Tanaka M, Matsuo O. A synthetic peptide derived from staphylokinase enhances plasminogen activation by tissue-type plasminogen activator J Thromb Haemost. 2011 May;9(5):997-1006.
5: Kulisek ES, Holm SE, Johnston KH. A chromogenic assay for the detection of plasmin generated by plasminogen activator immobilized on nitrocellulose using a para-nitroanilide synthetic peptide substrate Anal Biochem. 1989 Feb 15;177(1):78-84.
6: Wang-Lee JL, Lenhart JA, Ohleth KM, Ryan PL, Bagnell CA. Regulation of urokinase- and tissue-type plasminogen activator by relaxin in the uterus and cervix of the prepubertal gilt J Reprod Fertil. 1998 Sep;114(1):119-25.
7: Zhuang P, Wo D, Xu ZG, Wei W, Mao HM. Dynamic changes in plasma tissue plasminogen activator, plasminogen activator inhibitor-1 and beta-thromboglobulin content in ischemic stroke J Clin Neurosci. 2015 Jul;22(7):1123-7.
8: Kuusela P, Ullberg M, Saksela O, Kronvall G. Tissue-type plasminogen activator-mediated activation of plasminogen on the surface of group A, C, and G streptococci Infect Immun. 1992 Jan;60(1):196-201.
9: de Souza LR, M Melo P, Paschoalin T, Carmona AK, Kondo M, Hirata IY, Blaber M, Tersariol I, Takatsuka J, Juliano MA, Juliano L, Gomes RA, Puzer L. Human tissue kallikreins 3 and 5 can act as plasminogen activator releasing active plasmin Biochem Biophys Res Commun. 2013 Apr 12;433(3):333-7.
10: Rouy D, Anglés-Cano E. The mechanism of activation of plasminogen at the fibrin surface by tissue-type plasminogen activator in a plasma milieu in vitro. Role of alpha 2-antiplasmin Biochem J. 1990 Oct 1;271(1):51-7.

Products Related to Tissue Plasminogen Activator Chromogenic Substrate can be found at Substrates

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