Thrombin Bovine (Highly Pure)

Description

Thrombin Bovine (Highly Pure)
Catalog number: B2012286
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 2 kU
Molecular Weight or Concentration: NA
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20C
Keywords: Coagulation Factor II (Thrombin), Prepro-Coagulation Factor II, Coagulation Factor II, Prothrombin B-Chain, Serine Protease, Prothrombin
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Crean S, Michels SL, Moschella K, Reynolds MW. Bovine thrombin safety reporting: an example of study design and publication bias J Surg Res. 2010 Jan;158(1):77-86.
2: Crean SM, Michels SL, Reynolds MW. Exogenous bovine_thrombin as a biomarker of exposure and outcome Expert Rev Mol Diagn. 2008 Sep;8(5):651-61.
3: Ofosu FA, Crean S, Reynolds MW. A safety review of topical bovine_thrombin-induced generation of antibodies to bovine proteins Clin Ther. 2009 Apr;31(4):679-91.
4: Clark J, Crean S, Reynolds MW. Topical bovine thrombin and adverse events: a review of the literature Curr Med Res Opin. 2008 Jul;24(7):2071-87.
5: Clark JA, Humphries JE, Crean S, Reynolds MW. Topical bovine thrombin: a 21-year review of topical bovine_thrombin spontaneous case safety reports submitted to FDA’s Adverse Event Reporting System Pharmacoepidemiol Drug Saf. 2010 Feb;19(2):107-14.
6: Lundblad RL, Kingdon HS, Mann KG. Thrombin_ Methods Enzymol. 1976;45:156-76.
7: Rosenberg RD, Waugh DF. Multiple bovine thrombin components J Biol Chem. 1970 Oct 10;245(19):5049-56.
8: Shuman MA, Tollefsen DM, Majerus PW. The binding of human and bovine_thrombin to human platelets Blood. 1976 Jan;47(1):43-54.
9: Zhang Y, Li X, Zou R, Xue Y, Lou X, He M. Bovine_thrombin enhances the efficiency and specificity of polymerase chain reaction Biotechniques. 2014 Dec 1;57(6):289-94.
10: Fenton JW 2nd, Bing DH. Thrombin active-site regions Semin Thromb Hemost. 1986 Jul;12(3):200-8.

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