Tetramethylrhodamine Methyl Ester Perchlorate


Catalog Number: B2011121 (5 mg)
Tetramethylrhodamine Methyl Ester Perchlorate is a high quality positively charged cell-permeant red fluorescent dye that can be captured by active mitochondria. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Tetramethylrhodamine Methyl Ester Perchlorate
Catalog number: B2011121
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: N/A
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: 2-8 °C
Keywords: TMRM
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Fernandez-Mosquera L, Yambire KF, Couto R, Pereyra L, Pabis K, Ponsford AH, Diogo CV, Stagi M, Milosevic I, Raimundo N. Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis Autophagy. 2019 Sep;15(9):1572-1591.
2: Uribe P, Villegas JV, Boguen R, Treulen F, Sánchez R, Mallmann P, Isachenko V, Rahimi G, Isachenko E. Use of the fluorescent dye tetramethylrhodamine methyl ester perchlorate for mitochondrial membrane potential assessment in human spermatozoa Andrologia. 2017 Nov;49(9).
3: Meyer N, Zielke S, Michaelis JB, Linder B, Warnsmann V, Rakel S, Osiewacz HD, Fulda S, Mittelbronn M, Münch C, Behrends C, Kögel D. AT 101 induces early mitochondrial dysfunction and HMOX1 (heme oxygenase 1) to trigger mitophagic cell death in glioma cells Autophagy. 2018;14(10):1693-1709.
4: Wang CN, Pan HC, Lin YL, Chi CW, Shiao YJ. Ester derivatives of tournefolic acid B attenuate N-methyl-D-aspartate-mediated excitotoxicity in rat cortical neurons Mol Pharmacol. 2006 Mar;69(3):950-9.
5: Kim HY, Jeon H, Kim H, Koo S, Kim S. Sophora flavescens Aiton Decreases MPP(+)-Induced Mitochondrial Dysfunction in SH-SY5Y Cells Front Aging Neurosci. 2018 Apr 24;10:119.
6: Lan W, Lin J, Liu W, Wang F, Xie Y. Sulfiredoxin-1 protects spinal cord neurons against oxidative stress in the oxygen-glucose deprivation/reoxygenation model through the bax/cytochrome c/caspase 3 apoptosis pathway Neurosci Lett. 2021 Jan 23;744:135615.
7: Treulen F, Arias ME, Aguila L, Uribe P, Felmer R. Cryopreservation induces mitochondrial permeability transition in a bovine sperm model Cryobiology. 2018 Aug;83:65-74.
8: Uribe P, Meriño J, Manquemilla E, Villagrán C, Vega E, Zambrano F, Schulz M, Pezo F, Villegas JV, Boguen R, Sánchez R. Multiparameter Flow Cytometry Assay for Analysis of Nitrosative Stress Status in Human Spermatozoa Cytometry A. 2020 Dec;97(12):1238-1247.
9: Zadorozhnyi I, Hlukhova H, Kutovyi Y, Handziuk V, Naumova N, Offenhaeusser A, Vitusevich S. Towards pharmacological treatment screening of cardiomyocyte cells using Si nanowire FETs Biosens Bioelectron. 2019 Jul 15;137:229-235.
10: Hattori F, Chen H, Yamashita H, Tohyama S, Satoh YS, Yuasa S, Li W, Yamakawa H, Tanaka T, Onitsuka T, Shimoji K, Ohno Y, Egashira T, Kaneda R, Murata M, Hidaka K, Morisaki T, Sasaki E, Suzuki T, Sano M, Makino S, Oikawa S, Fukuda K. Nongenetic method for purifying stem cell-derived cardiomyocytes Nat Methods. 2010 Jan;7(1):61-6.

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Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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