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Syk Kinase Peptide Substrate

$495.00

Catalog Number: B2011502 (1 mg)
Syk Kinase Peptide Substrate is a high quality synthetic substrate for Syk kinase. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2011502 Categories: ,

Description

Syk Kinase Peptide Substrate
Catalog number: B2011502
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 1463.6 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: Syk Kinase Peptide System
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Lipchik AM, Killins RL, Geahlen RL, Parker LL. A peptide-based biosensor assay to detect intracellular Syk kinase activation and inhibition Biochemistry. 2012 Sep 25;51(38):7515-24.
2: Uckun FM, Qazi S, Ma H, Tuel-Ahlgren L, Ozer Z. STAT3 is a substrate of SYK tyrosine kinase in B-lineage leukemia/lymphoma cells exposed to oxidative stress Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):2902-7.
3: Kim JY, Huh K, Jung R, Kim TJ. Identification of BCAR-1 as a new substrate of Syk tyrosine kinase through a determination of amino acid sequence preferences surrounding the substrate tyrosine residue Immunol Lett. 2011 Mar 30;135(1-2):151-7.
4: Yamamoto N, Hasegawa H, Seki H, Ziegelbauer K, Yasuda T. Development of a high-throughput fluoroimmunoassay for Syk kinase and Syk kinase inhibitors Anal Biochem. 2003 Apr 15;315(2):256-61.
5: Yi YS, Kim HG, Kim JH, Yang WS, Kim E, Jeong D, Park JG, Aziz N, Kim S, Parameswaran N, Cho JY. Syk-MyD88 Axis Is a Critical Determinant of Inflammatory-Response in Activated Macrophages Front Immunol. 2021 Dec 23;12:767366.
6: Yu S, Huang H, Iliuk A, Wang WH, Jayasundera KB, Tao WA, Post CB, Geahlen RL. Syk inhibits the activity of protein kinase A by phosphorylating tyrosine 330 of the catalytic subunit J Biol Chem. 2013 Apr 12;288(15):10870-81.
7: de Castro RO, Zhang J, Jamur MC, Oliver C, Siraganian RP. Tyrosines in the carboxyl terminus regulate Syk kinase activity and function J Biol Chem. 2010 Aug 20;285(34):26674-84.
8: Kulathu Y, Hobeika E, Turchinovich G, Reth M. The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development EMBO J. 2008 May 7;27(9):1333-44.
9: Lau C, Wang X, Song L, North M, Wiehler S, Proud D, Chow CW. Syk associates with clathrin and mediates phosphatidylinositol 3-kinase activation during human rhinovirus internalization J Immunol. 2008 Jan 15;180(2):870-80.
10: Kulathu Y, Grothe G, Reth M. Autoinhibition and adapter function of Syk Immunol Rev. 2009 Nov;232(1):286-99.

Products Related to Syk Kinase Peptide Substrate can be found at Substrates

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