Sodium Cholate Hydrate (Powder)


Catalog Number: B2010155 (1 g)
Sodium cholate hydrate is a high quality research product used as multipurpose non-denaturing detergent widely used in the biochemistry of protein extraction and purification. It has been especially used with membrane proteins. Custom bulk orders of this product are available upon request.

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SKU: B2010155 Categories: ,


Sodium cholate hydrate
Catalog number: B2010155
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 1 g
pH: na
Supplied as: Ready-to-use
Appearance: White Powder
Applications: multipurpose non-denaturing detergent widely used in the biochemistry of protein extraction and purification. It has been especially used with membrane proteins.
Storage: Room temperature
Keywords: 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt, Cholalic acid sodium salt
Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.

1: Wu Z, Yang C, Chen L, Ma L, Wu X, Dai X, Qiao Y, Shi X. A Multiscale Study on
the Effect of Sodium Cholate on the Deformation Ability of Elastic Liposomes.
AAPS PharmSciTech. 2019 Sep 13;20(8):311.

2: Ma L, Wang X, Wu J, Zhang D, Zhang L, Song X, Hong H, He C, Mo X, Wu S, Kai
G, Wang H. Polyethylenimine and sodium cholate-modified ethosomes complex as
multidrug carriers for the treatment of melanoma through transdermal delivery.
Nanomedicine (Lond). 2019 Sep;14(18):2395-2408.

3: Zhang X, Wu Y, Zhang M, Mao J, Wu Y, Zhang Y, Yao J, Xu C, Guo W, Yu B.
Sodium cholate-enhanced polymeric micelle system for tumor-targeting delivery of
paclitaxel. Int J Nanomedicine. 2017 Dec 13;12:8779-8799.

4: Ruiz-Canizales J, Domínguez-Avila JA, Wall-Medrano A, Ayala-Zavala JF,
González-Córdova AF, Vallejo-Córdoba B, Salazar-López NJ, González-Aguilar GA.
Fiber and phenolic compounds contribution to the hepatoprotective effects of
mango diets in rats fed high cholesterol/sodium cholate. Phytother Res. 2019

5: Jiang S, Mou Y, He H, Yang D, Qin L, Zhang F, Zhang P. Preparation and
evaluation of self-assembly Soluplus®-sodium cholate-phospholipid
ternary mixed micelles of docetaxel. Drug Dev Ind Pharm. 2019

6: Chen M, Chang R, Xu L, Huang Y, Zhang H, Chen A. Simultaneous separation and
determination of praeruptorin A, B and C by micellar electrokinetic
chromatography using sodium dodecyl sulphate and sodium cholate as mixed
micelles. Phytochem Anal. 2018 Sep;29(5):425-431.

7: Chandirasekar S, Chandrasekaran C, Muthukumarasamyvel T, Sudhandiran G,
Rajendiran N. Sodium cholat-templated blue light-emitting Ag subnanoclusters:
in vivo toxicity and imaging in zebrafish embryos. ACS Appl Mater Interfaces.
2015 Jan 28;7(3):1422-30.

8: Zhu Y, Yu J, Tong S, Wang L, Peng M, Cao X, Xu X. Preparation and in vitro
evaluation of povidone-sodium cholate-phospholipid mixed micelles for the
solubilization of poorly soluble drugs. Arch Pharm Res. 2010 Jun;33(6):911-7.

9: Sugioka H, Moroi Y. Micelle formation of sodium cholat and solubilization
into the micelle. Biochim Biophys Acta. 1998 Oct 2;1394(1):99-110.

10: Danielsen EM, Hansen GH. Probing the Action of Permeation Enhancers Sodium
Cholate and N-dodecyl-β-D-maltoside in a Porcine Jejunal Mucosal Explant System.
Pharmaceutics. 2018 Oct 2;10(4):172.

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