Single Donor Human Sickle Cell Serum


Catalog Number: B2014024 (1 mL)
Single Donor Human Sickle Cell Serum is a high quality Single Donor Human Sickle Cell Serum. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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Single Donor Human Sickle Cell Serum
Catalog number: B2014024
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mL
Molecular Weight or Concentration: N/A
Supplied as: Serum
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: Single Donor Human Sickle Cell Serum
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Lattanzi A, Camarena J, Lahiri P, Segal H, Srifa W, Vakulskas CA, Frock RL, Kenrick J, Lee C, Talbott N, Skowronski J, Cromer MK, Charlesworth CT, Bak RO, Mantri S, Bao G, DiGiusto D, Tisdale J, Wright JF, Bhatia N, Roncarolo MG, Dever DP, Porteus MH. Development of _-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease Sci Transl Med. 2021 Jun 16;13(598):eabf2444.
2: Jain V, Yang WH, Wu J, Roback JD, Gregory SG, Chi JT. Single Cell RNA-Seq Analysis of Human Red Cells Front Physiol. 2022 Apr 20;13:828700.
3: Magrin E, Semeraro M, Hebert N, Joseph L, Magnani A, Chalumeau A, Gabrion A, Roudaut C, Marouene J, Lefrere F, Diana JS, Denis A, Neven B, Funck-Brentano I, Negre O, Renolleau S, Brousse V, Kiger L, Touzot F, Poirot C, Bourget P, El Nemer W, Blanche S, Trluyer JM, Asmal M, Walls C, Beuzard Y, Schmidt M, Hacein-Bey-Abina S, Asnafi V, Guichard I, Poire M, Monpoux F, Touraine P, Brouzes C, de Montalembert M, Payen E, Six E, Ribeil JA, Miccio A, Bartolucci P, Leboulch P, Cavazzana M. Long-term outcomes of lentiviral gene therapy for the _-hemoglobinopathies: the HGB-205 trial Nat Med. 2022 Jan;28(1):81-88.
4: Mtais JY, Doerfler PA, Mayuranathan T, Bauer DE, Fowler SC, Hsieh MM, Katta V, Keriwala S, Lazzarotto CR, Luk K, Neel MD, Perry SS, Peters ST, Porter SN, Ryu BY, Sharma A, Shea D, Tisdale JF, Uchida N, Wolfe SA, Woodard KJ, Wu Y, Yao Y, Zeng J, Pruett-Miller S, Tsai SQ, Weiss MJ. Genome editing of HBG1 and HBG2 to induce fetal hemoglobin Blood Adv. 2019 Nov 12;3(21):3379-3392.
5: Douglass PM, O’Connor T, Javidi B. Automated sickle cell disease identification in human red blood cells using a lensless single random phase encoding biosensor and convolutional neural networks Opt Express. 2022 Sep 26;30(20):35965-35977.
6: Martin RM, Ikeda K, Cromer MK, Uchida N, Nishimura T, Romano R, Tong AJ, Lemgart VT, Camarena J, Pavel-Dinu M, Sindhu C, Wiebking V, Vaidyanathan S, Dever DP, Bak RO, Laustsen A, Lesch BJ, Jakobsen MR, Sebastiano V, Nakauchi H, Porteus MH. Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination Cell Stem Cell. 2019 May 2;24(5):821-828.e5.
7: Romero Z, Lomova A, Said S, Miggelbrink A, Kuo CY, Campo-Fernandez B, Hoban MD, Masiuk KE, Clark DN, Long J, Sanchez JM, Velez M, Miyahira E, Zhang R, Brown D, Wang X, Kurmangaliyev YZ, Hollis RP, Kohn DB. Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates Mol Ther. 2019 Aug 7;27(8):1389-1406.
8: DeWitt MA, Magis W, Bray NL, Wang T, Berman JR, Urbinati F, Heo SJ, Mitros T, Muoz DP, Boffelli D, Kohn DB, Walters MC, Carroll D, Martin DI, Corn JE. Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells Sci Transl Med. 2016 Oct 12;8(360):360ra134.
9: Nickel RS, Flegel WA, Adams SD, Hendrickson JE, Liang H, Tisdale JF, Hsieh MM. The impact of pre-existing HLA and red blood cell antibodies on transfusion support and engraftment in sickle cell disease after nonmyeloablative hematopoietic stem cell transplantation from HLA-matched sibling donors: A prospective, single-center, observational study EClinicalMedicine. 2020 Jun 28;24:100432.
10: Allen ES, Srivastava K, Hsieh MM, Fitzhugh CD, Klein HG, Tisdale JF, Flegel WA. Immunohaematological complications in patients with sickle cell disease after haemopoietic progenitor cell transplantation: a prospective, single-centre, observational study Lancet Haematol. 2017 Nov;4(11):e553-e561.

Products Related to Single Donor Human Sickle Cell Serum can be found at Biofluids

Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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