Prostate Specific Antigen Substrate

Description

Prostate Specific Antigen Substrate
Catalog number: B2012880
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: N/A
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: KLK3, Kallikrein-related peptidase-3, PSA
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: LeBeau AM, Singh P, Isaacs JT, Denmeade SR. Prostate-specific antigen is a “chymotrypsin-like” serine protease with unique P1 substrate specificity Biochemistry. 2009 Apr 21;48(15):3490-6.
2: Coombs GS, Bergstrom RC, Pellequer JL, Baker SI, Navre M, Smith MM, Tainer JA, Madison EL, Corey DR. Substrate specificity of prostate-specific antigen (PSA) Chem Biol. 1998 Sep;5(9):475-88.
3: Anderson MO, Wu LY, Santiago NM, Moser JM, Rowley JA, Bolstad ES, Berkman CE. Substrate specificity of prostate-specific membrane antigen Bioorg Med Chem. 2007 Nov 1;15(21):6678-86.
4: Bakthavatsalam S, Wiangnak P, George DJ, Zhang T, Franz KJ. Dithiocarbamate prodrugs activated by prostate specific antigen to target prostate cancer Bioorg Med Chem Lett. 2020 Jun 1;30(11):127148.
5: Singh P, LeBeau AM, Lilja H, Denmeade SR, Isaacs JT. Molecular insights into substrate specificity of prostate specific antigen through structural modeling Proteins. 2009 Dec;77(4):984-93.
6: Wu LY, Johnson JM, Simmons JK, Mendes DE, Geruntho JJ, Liu T, Dirksen WP, Rosol TJ, Davis WC, Berkman CE. Biochemical characterization of prostate-specific membrane antigen from canine prostate carcinoma cells Prostate. 2014 May;74(5):451-7.
7: Aloysius H, Hu L. Improving the Specificity of the Prostate-Specific Antigen_Substrate Glutaryl-Hyp-Ala-Ser-Chg-Gln as a Promoiety Chem Biol Drug Des. 2015 Oct;86(4):837-48.
8: Patanè S. Prostate-specific antigen kallikrein and the heart World J Cardiol. 2009 Dec 31;1(1):23-5.
9: Nagar R, Sharma KK. Prostate specific antigen in cord blood Indian J Clin Biochem. 2012 Oct;27(4):375-8.
10: Conway RE, Rojas C, Alt J, Nováková Z, Richardson SM, Rodrick TC, Fuentes JL, Richardson NH, Attalla J, Stewart S, Fahmy B, Barinka C, Ghosh M, Shapiro LH, Slusher BS. Prostate-specific membrane antigen (PSMA)-mediated laminin proteolysis generates a pro-angiogenic peptide Angiogenesis. 2016 Oct;19(4):487-500.

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