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Poly-L-histidine (Highly Pure)

Original price was: $2,795.00.Current price is: $1,395.00.

Catalog Number: B2018760 (50 mg)
Poly-L-histidine is a synthetic polymer composed of multiple units of the amino acid histidine linked together. It is often used in research and biotechnology applications due to its ability to bind to metals and other molecules. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

5/5 - (1 vote)

Poly-L-histidine (Highly Pure)
Catalog number: B2018760
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 mg
Molecular Weight or Concentration: 5,000-25,000
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: L-Histidine homopolymer
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Zhang Y, Kim I, Lu Y, Xu Y, Yu DG, Song W. Intelligent poly(l-histidine)-based nanovehicles for controlled drug delivery J Control Release. 2022 Sep;349:963-982.
2: Kastania AS, Petrou PS, Loukas CM, Gogolides E. Poly-L-histidine coated microfluidic devices for bacterial DNA purification without chaotropic solutions Biomed Microdevices. 2020 Jun 22;22(3):44.
3: Honda R, Yamaguchi KI, Elhelaly AE, Fuji M, Kuwata K. Poly-L-histidine inhibits prion propagation in a prion-infected cell line Prion. 2018;12(3-4):226-233.
4: Wahane A, Malik S, Shih KC, Gaddam RR, Chen C, Liu Y, Nieh MP, Vikram A, Bahal R. Dual-Modality Poly-l-histidine Nanoparticles to Deliver Peptide Nucleic Acids and Paclitaxel for In Vivo Cancer Therapy ACS Appl Mater Interfaces. 2021 Sep 29;13(38):45244-45258.
5: Yang CJ, Nguyen DD, Lai JY. Poly(l-Histidine)-Mediated On-Demand Therapeutic Delivery of Roughened Ceria Nanocages for Treatment of Chemical Eye Injury Adv Sci (Weinh). 2023 Sep;10(26):e2302174.
6: Haghi A, Raissi H, Hashemzadeh H, Farzad F. Development of the poly(l-histidine) grafted carbon nanotube as a possible smart drug delivery vehicle Comput Biol Med. 2022 Apr;143:105336.
7: Augustine R, Kim DK, Kim HA, Kim JH, Kim I. Poly(N-isopropylacrylamide)-b-Poly(L-lysine)-b-Poly(L-histidine) Triblock Amphiphilic Copolymer Nanomicelles for Dual-Responsive Anticancer Drug Delivery J Nanosci Nanotechnol. 2020 Nov 1;20(11):6959-6967.
8: Wang P, Liu W, Liu S, Yang R, Pu Y, Zhang W, Wang X, Liu X, Ren Y, Chi B. pH-responsive nanomicelles of poly(ethylene glycol)-poly(ε-caprolactone)-poly(L-histidine) for targeted drug delivery J Biomater Sci Polym Ed. 2020 Feb;31(3):277-292.
9: Johnson RP, Chung CW, Jeong YI, Kang DH, Suh H, Kim I. Poly(L-histidine)-tagged 5-aminolevulinic acid prodrugs: new photosensitizing precursors of protoporphyrin IX for photodynamic colon cancer therapy Int J Nanomedicine. 2012;7:2497-512.
10: Asayama S, Hamaya A, Sekine T, Kawakami H, Nagaoka S. Aminated poly(L-histidine) as new pH-sensitive DNA carrier Nucleic Acids Symp Ser (Oxf). 2004;(48):229-30.

Products Related to Poly-L-histidine (Highly Pure) can be found at Chemicals

Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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