PKG Substrate Glasstide

Product Description

PKG Substrate Glasstide
Catalog number: B2011347
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 902.1 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: protein kinase G susbtrate
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Plano SA, Alessandro MS, Trebucq LL, Endo S, Golombek DA, Chiesa JJ. Role of G-Substrate in the NO/cGMP/PKG Signal Transduction Pathway for Photic Entrainment of the Hamster Circadian Clock ASN Neuro. 2021 Jan-Dec;13:1759091420984920.
2: Endo S. G-substrate: the cerebellum and beyond Prog Mol Biol Transl Sci. 2012;106:381-416.
3: Schlossmann J, Desch M. IRAG and novel PKG targeting in the cardiovascular system Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H672-82.
4: Morone PJ, Yan W, Adcock J, Komalavilas P, Mocco J, Thompson RC, Brophy C, Cheung-Flynn J. Vasorelaxing cell permeant phosphopeptide mimetics for subarachnoid hemorrhage Eur J Pharmacol. 2021 Jun 5;900:174038.
5: Smolenski A. Novel roles of cAMP/cGMP-dependent signaling in platelets J Thromb Haemost. 2012 Feb;10(2):167-76.
6: Alverdi V, Mazon H, Versluis C, Hemrika W, Esposito G, van den Heuvel R, Scholten A, Heck AJ. cGMP-binding prepares PKG for substrate binding by disclosing the C-terminal domain J Mol Biol. 2008 Feb 1;375(5):1380-93.
7: Nakazawa T, Endo S, Shimura M, Kondo M, Ueno S, Tamai M. Retinal G-substrate, potential downstream component of NO/cGMP/PKG pathway, is located in subtype of retinal ganglion cells and amacrine cells with protein phosphatases Brain Res Mol Brain Res. 2005 Apr 27;135(1-2):58-68.
8: Li L, Li L, Chen C, Yang J, Li J, Hu N, Li Y, Zhang D, Guo T, Liu X, Yang W. Scutellarin’s Cardiovascular Endothelium Protective Mechanism: Important Role of PKG-Iα PLoS One. 2015 Oct 6;10(10):e0139570.
9: Kim C, Sharma R. Cyclic nucleotide selectivity of protein kinase G isozymes Protein Sci. 2021 Feb;30(2):316-327.
10: Engin A. Human Protein Kinases and Obesity Adv Exp Med Biol. 2017;960:111-134.

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