PEG 3350 (Biochemistry Grade)

Product Description

PEG 3350
Catalog number: B2010063
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 50 g
pH: na
Supplied as: Ready-to-use
Appearance: White Powder
Applications: hydrophylic polymer with a 3350 MW average. PEG 3350 has been used as crowding agent in immunoturbidimetric assays as well as component of crystallization buffers.
Storage: Room temperature
Keywords: Polyethylene Glycol, Macrogol
Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.

References:
1: Williams KC, Rogers LK, Hill I, Barnard J, Di Lorenzo C. PEG 3350
Administration Is Not Associated with Sustained Elevation of Glycol Levels. J
Pediatr. 2018 Apr;195:148-153.e1.

2: Jarzebicka D, Sieczkowska-Golub J, Kierkus J, Czubkowski P, Kowalczuk-Kryston
M, Pelc M, Lebensztejn D, Korczowski B, Socha P, Oracz G. PEG 3350 Versus
Lactulose for Treatment of Functional Constipation in Children: Randomized
Study. J Pediatr Gastroenterol Nutr. 2019 Mar;68(3):318-324.

3: Brenner DM, Hu Y, Datto C, Creanga D, Camilleri M. A Randomized, Multicenter,
Prospective, Crossover, Open-Label Study of Factors Associated With Patient
Preferences for Naloxegol or PEG 3350 for Opioid-Induced Constipation. Am J
Gastroenterol. 2019 Jun;114(6):954-963.

4: Rahimi RS, Singal AG, Cuthbert JA, Rockey DC. Lactulose vs polyethylene
glycol 3350–electrolyte solution for treatment of overt hepatic encephalopathy:
the HELP randomized clinical trial. JAMA Intern Med. 2014 Nov;174(11):1727-33.

5: Tutar E, Bayrak NA, Volkan B, Ertem D. Bowel Preparation for Colonoscopy in
Children: 1 Day PEG-3350 with Bisacodyl versus 3 Day Sennosides. Dig Dis.
2019;37(4):334-342.

6: Khan MA, Patel KB, Nooruddin M, Swanson G, Fogg L, Keshavarzian A, Brown M.
Polyethylene Glycol-3350 (Miralax®)+1.9-L sports drink (Gatorade®)+2 tablets of
bisacodyl results in inferior bowel preparation for colonoscopy compared with
Polyethylene Glycol-Ascorbic Acid (MoviPrep®). Turk J Gastroenterol. 2018
Jan;29(1):67-74.

7: Stone CA Jr, Liu Y, Relling MV, Krantz MS, Pratt AL, Abreo A, Hemler JA,
Phillips EJ. Immediate Hypersensitivity to Polyethylene Glycols and
Polysorbates: More Common Than We Have Recognized. J Allergy Clin Immunol Pract.
2019 May-Jun;7(5):1533-1540.e8.

8: Chapman RW, Stanghellini V, Geraint M, Halphen M. Randomized clinical trial:
macrogol/PEG 3350 plus electrolytes for treatment of patients with constipation
associated with irritable bowel syndrome. Am J Gastroenterol. 2013
Sep;108(9):1508-15.

9: Cinca R, Chera D, Gruss HJ, Halphen M. Randomised clinical trial:
macrogol/PEG 3,350+electrolytes versus prucalopride in the treatment of chronic
constipation — a comparison in a controlled environment. Aliment Pharmacol
Ther. 2013 May;37(9):876-86.

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