Neutrophil Elastase Substrate

Description

Neutrophil Elastase Substrate
Catalog number: B2011340
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 681.7 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: hNE Substrate
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Jugniot N, Voisin P, Bentaher A, Mellet P. Neutrophil Elastase Activity Imaging: Recent Approaches in the Design and Applications of Activity-Based Probes and Substrate-Based Probes Contrast Media Mol Imaging. 2019 Jun 12;2019:7417192.
2: Sato T, Takahashi S, Mizumoto T, Harao M, Akizuki M, Takasugi M, Fukutomi T, Yamashita J. Neutrophil elastase and cancer Surg Oncol. 2006 Dec;15(4):217-22.
3: Leahy D, Grant C, Jackson A, Duff A, Tardiota N, Van Haeften J, Chen X, Peake JM, Kruppa MD, Smith ET, Johnson DA, Lott WB, Harris JM. Discrimination of Methionine Sulfoxide and Sulfone by Human Neutrophil Elastase Molecules. 2021 Sep 2;26(17):5344.
4: Ogura Y, Tajiri K, Murakoshi N, Xu D, Yonebayashi S, Li S, Okabe Y, Feng D, Shimoda Y, Song Z, Mori H, Yuan Z, Aonuma K, Ieda M. Neutrophil Elastase Deficiency Ameliorates Myocardial Injury Post Myocardial Infarction in Mice Int J Mol Sci. 2021 Jan 13;22(2):722.
5: Moroy G, Alix AJ, Sapi J, Hornebeck W, Bourguet E. Neutrophil elastase as a target in lung cancer Anticancer Agents Med Chem. 2012 Jul;12(6):565-79.
6: Ungurs MJ, Sinden NJ, Stockley RA. Progranulin is a substrate for neutrophil-elastase and proteinase-3 in the airway and its concentration correlates with mediators of airway inflammation in COPD Am J Physiol Lung Cell Mol Physiol. 2014 Jan 1;306(1):L80-7.
7: Kunder M, Lakshmaiah V, Moideen Kutty AV. Plasma Neutrophil Elastase, α(1)-Antitrypsin, α(2)-Macroglobulin and Neutrophil Elastase-α(1)-Antitrypsin Complex Levels in patients with Dengue Fever Indian J Clin Biochem. 2018 Apr;33(2):218-221.
8: Yang T, Pan SC, Cheng CM. Paper-based human neutrophil elastase detection device for clinical wound monitoring Lab Chip. 2020 Aug 7;20(15):2709-2716.
9: Döring G. The role of neutrophil elastase in chronic inflammation Am J Respir Crit Care Med. 1994 Dec;150(6 Pt 2):S114-7.
10: Chalmers JD, Moffitt KL, Suarez-Cuartin G, Sibila O, Finch S, Furrie E, Dicker A, Wrobel K, Elborn JS, Walker B, Martin SL, Marshall SE, Huang JT, Fardon TC. Neutrophil Elastase Activity Is Associated with Exacerbations and Lung Function Decline in Bronchiectasis Am J Respir Crit Care Med. 2017 May 15;195(10):1384-1393.

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