Native Horse Butyrylcholinesterase

Product Description

Native Horse Butyrylcholinesterase
Catalog number: B2016553
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 2 kU
Molecular Weight or Concentration: N/A
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: Carboxylic ester hydrolase, butyrylcholinesterase, BCHE
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Cauet G, Friboulet A, Thomas D. Substrate activation and thermal denaturation kinetics of the tetrameric and the trypsin-generated monomeric forms of horse serum butyrylcholinesterase Biochim Biophys Acta. 1987 Apr 30;912(3):338-42.
2: Li H, Schopfer LM, Masson P, Lockridge O. Lamellipodin proline rich peptides associated with native plasma butyrylcholinesterase tetramers Biochem J. 2008 Apr 15;411(2):425-32.
3: Ganeshpurkar A, Singh R, Kumar D, Gutti G, Sardana D, Shivhare S, Singh RB, Kumar A, Singh SK. Development of homology model, docking protocol and Machine-Learning based scoring functions for identification of Equus caballus’s butyrylcholinesterase inhibitors J Biomol Struct Dyn. 2022;40(24):13693-13710.
4: Wierdl M, Morton CL, Danks MK, Potter PM. Isolation and characterization of a cDNA encoding a horse liver butyrylcholinesterase: evidence for CPT-11 drug activation Biochem Pharmacol. 2000 Apr 1;59(7):773-81.
5: Peng H, Brimijoin S, Hrabovska A, Krejci E, Blake TA, Johnson RC, Masson P, Lockridge O. Monoclonal antibodies to human butyrylcholinesterase reactive with butyrylcholinesterase in animal plasma Chem Biol Interact. 2016 Jan 5;243:82-90.
6: Zhang P, Jain P, Tsao C, Sinclair A, Sun F, Hung HC, Bai T, Wu K, Jiang S. Butyrylcholinesterase nanocapsule as a long circulating bioscavenger with reduced immune response J Control Release. 2016 May 28;230:73-8.
7: Eriksson H, Augustinsson KB. A mechanistic model for butyrylcholinesterase Biochim Biophys Acta. 1979 Mar 16;567(1):161-73.
8: Saxena A, Qian N, Kovach IM, Kozikowski AP, Pang YP, Vellom DC, Radić Z, Quinn D, Taylor P, Doctor BP. Identification of amino acid residues involved in the binding of Huperzine A to cholinesterases Protein Sci. 1994 Oct;3(10):1770-8.
9: Saxena A, Raveh L, Ashani Y, Doctor BP. Structure of glycan moieties responsible for the extended circulatory life time of fetal bovine serum acetylcholinesterase and equine serum butyrylcholinesterase Biochemistry. 1997 Jun 17;36(24):7481-9.
10: Gentry MK, Saxena A, Ashani Y, Doctor BP. Immunochemical characterization of anti-acetylcholinesterase inhibitory monoclonal antibodies Chem Biol Interact. 1993 Jun;87(1-3):227-31.

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