Sale!

N-tetradecanoyl-L-homoserine Lactone

Original price was: $1,595.00.Current price is: $795.00.

Catalog Number: B2017910 (5 mg)
N-tetradecanoyl-L-homoserine lactone (C14-HSL) is a type of signaling molecule known as a homoserine lactone. It is commonly produced by certain bacteria as a means of communication in a process called quorum sensing. Quorum sensing allows bacteria to coordinate their behavior based on population density, regulating processes such as biofilm formation, virulence factor production, and other behaviors. C14-HSL specifically is produced by various Gram-negative bacteria and plays a role in regulating gene expression and coordinating group behaviors. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

In stock

SKU: B2017910 Categories: , Tag:

Product Description

5/5 - (2 votes)

N-tetradecanoyl-L-homoserine Lactone
Catalog number: B2017910
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 311.46
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: (S)-N-(2-oxotetrahydrofuran-3-yl)tetradecanamide
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Tobita N, Tsuneto K, Ito S, Yamamoto T. Human TRPV1 and TRPA1 are receptors for bacterial quorum sensing molecules J Biochem. 2022 Jan 7;170(6):775-785.
2: Kher HL, Krishnan T, Letchumanan V, Hong KW, How KY, Lee LH, Tee KK, Yin WF, Chan KG. Characterization of quorum sensing genes and N-acyl homoserine lactones in Citrobacter amalonaticus strain YG6 Gene. 2019 Feb 5;684:58-69.
3: Feng Z, Lu X, Chen C, Huo Y, Zhou D. Transboundary intercellular communications between Penicillium and bacterial communities during sludge bulking: Inspirations on quenching fungal dominance Water Res. 2022 Aug 1;221:118829.
4: Qin X, Thota GK, Singh R, Balamurugan R, Goycoolea FM. Synthetic homoserine lactone analogues as antagonists of bacterial quorum sensing Bioorg Chem. 2020 May;98:103698.
5: Saurav K, Costantino V, Venturi V, Steindler L. Quorum Sensing Inhibitors from the Sea Discovered Using Bacterial N-acyl-homoserine Lactone-Based Biosensors Mar Drugs. 2017 Feb 23;15(3):53.
6: Zhang Q, Li S, Hachicha M, Boukraa M, Soulère L, Efrit ML, Queneau Y. Heterocyclic Chemistry Applied to the Design of N-Acyl Homoserine Lactone Analogues as Bacterial Quorum Sensing Signals Mimics Molecules. 2021 Aug 24;26(17):5135.
7: Parsek MR, Greenberg EP. Acyl-homoserine lactone quorum sensing in gram-negative bacteria: a signaling mechanism involved in associations with higher organisms Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):8789-93.
8: Fuqua C, Greenberg EP. Listening in on bacteria: acyl-homoserine lactone signalling Nat Rev Mol Cell Biol. 2002 Sep;3(9):685-95.
9: Shrestha A, Hernández-Reyes C, Grimm M, Krumwiede J, Stein E, Schenk ST, Schikora A. AHL-Priming Protein 1 mediates N-3-oxo-tetradecanoyl-homoserine lactone priming in Arabidopsis BMC Biol. 2022 Dec 5;20(1):268.
10: Lade H, Paul D, Kweon JH. N-acyl homoserine lactone-mediated quorum sensing with special reference to use of quorum quenching bacteria in membrane biofouling control Biomed Res Int. 2014;2014:162584.

Products Related to N-tetradecanoyl-L-homoserine Lactone can be found at Lipids

Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (2 votes)

Several ways to order Molecular Depot products:

1- Order online using our website’s automated shopping cart and checkout system (available 24/7).

2- Order by email: info@moleculardepot.com (we accept electronic PO, available 24/7).

3- Order by Live Chat.

4- Order by Fax: 1-858-437-9884 (available 24/7).

Â