N-(Benzyloxycarbonyloxy)succinimide

Product Description

N-(Benzyloxycarbonyloxy)succinimide
Catalog number: B2016196
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 g
Molecular Weight or Concentration: 249.22
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: RT, Dry
Keywords: Benzyl N-succinimidyl carbonate, Z-OSu
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
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2: Shiozaki M, Arai M, Hiraoka T, Nishijima M, Akamatsu Y. Synthesis of 2-deoxy-2-[(2R,3S)-2-fluoro-3-hydroxytetradecanamido]- 3-O-[(3R)-3-hydroxytetradecanoyl]-4-O-phosphono-D-glucopyranose and its (2S,3R)-isomer Biosci Biotechnol Biochem. 1993 Sep;57(9):1526-9.
3: Shiozaki M, Kobayashi Y, Arai M, Watanabe T, Hiraoka T. Synthesis of 2-deoxy-2-[(2,2-difluoro-3-hydroxytetradecanoyl)amino]-3-O- [(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glucopyranose 4-phosphate J Med Chem. 1991 Aug;34(8):2643-6.
4: Zhao Z, Yue J, Ji X, Nian M, Kang K, Qiao H, Zheng X. Research progress in biological activities of succinimide derivatives Bioorg Chem. 2021 Mar;108:104557.
5: Renaudet O, Dumy P, Philouze C, Averbuch-Pouchot MT. N-(2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-alpha-D-galactopyranosyloxy)succinimide Acta Crystallogr C. 2001 May;57(Pt 5):649-50.
6: Parsons WH, Rutland NT, Crainic JA, Cardozo JM, Chow AS, Andrews CL, Sheehan BK. Development of succinimide-based inhibitors for the mitochondrial rhomboid protease PARL Bioorg Med Chem Lett. 2021 Oct 1;49:128290.
7: Li YF, Wei YF, Tian J, Zhang J, Chang HH, Gao WC. N-Thiohydroxy Succinimide Esters (NTSEs): Versatile Reagents for Selective Acyl and Acylthio Transfer Org Lett. 2022 Aug 12;24(31):5736-5740.
8: Nowak C, Ponniah G, Neill A, Liu H. Characterization of succinimide stability during trypsin digestion for LC-MS analysis Anal Biochem. 2017 Jun 1;526:1-8.
9: VanAernum ZL, Sergi JA, Dey M, Toner T, Kilgore B, Lay-Fortenbery A, Wang Y, Bian S, Kochert BA, Bothe JR, Gao X, Richardson D, Schuessler HA. Discovery and Control of Succinimide Formation and Accumulation at Aspartic Acid Residues in The Complementarity-Determining Region of a Therapeutic Monoclonal Antibody Pharm Res. 2023 Jun;40(6):1411-1423.
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