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Mouse CCL2 Protein

Original price was: $1,595.00.Current price is: $795.00.

Catalog Number: B2011839 (50 µg)
Mouse CCL2 Protein is a high quality recombinant mouse CCL2 protein His tagged and expressed in E. coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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Product Description

Mouse CCL2 Protein
Catalog number: B2011839
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 µg
Molecular Weight or Concentration: 250 µg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: C-C motif chemokine 2 protein, AI323594 protein, HC11 protein, JE protein, MCAF protein, MCP-1 protein, MCP1 protein, Scya2 protein, Sigje protein, SMC-CF protein, CCL2, CCL 2, CCL-2
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Li X, Yuan B, Lu M, Wang Y, Ding N, Liu C, Gao M, Yao Z, Zhang S, Zhao Y, Xie L, Chen Z. The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression Nat Commun. 2021 Dec 10;12(1):7213.
2: He J, Song Y, Li G, Xiao P, Liu Y, Xue Y, Cao Q, Tu X, Pan T, Jiang Z, Cao X, Lai L, Wang Q. Fbxw7 increases CCL2/7 in CX3CR1hi macrophages to promote intestinal inflammation J Clin Invest. 2019 Jun 27;129(9):3877-3893.
3: Yang X, Lin Y, Shi Y, Li B, Liu W, Yin W, Dang Y, Chu Y, Fan J, He R. FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling Cancer Res. 2016 Jul 15;76(14):4124-35.
4: Liu B, Xiang L, Ji J, Liu W, Chen Y, Xia M, Liu Y, Liu W, Zhu P, Jin Y, Han Y, Lu J, Li X, Zheng M, Lu Y. Sparcl1 promotes nonalcoholic steatohepatitis progression in mice through upregulation of CCL2 J Clin Invest. 2021 Oct 15;131(20):e144801.
5: Gao J, Wei B, Liu M, Hirsova P, Sehrawat TS, Cao S, Hu X, Xue F, Yaqoob U, Kang N, Cui H, Pomerantz WCK, Kostallari E, Shah VH. Endothelial p300 Promotes Portal Hypertension and Hepatic Fibrosis Through C-C Motif Chemokine Ligand 2-Mediated Angiocrine Signaling Hepatology. 2021 Jun;73(6):2468-2483.
6: Petrasek J, Bala S, Csak T, Lippai D, Kodys K, Menashy V, Barrieau M, Min SY, Kurt-Jones EA, Szabo G. IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice J Clin Invest. 2012 Oct;122(10):3476-89.
7: Caesar R, Tremaroli V, Kovatcheva-Datchary P, Cani PD, Bäckhed F. Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling Cell Metab. 2015 Oct 6;22(4):658-68.
8: Semple BD, Frugier T, Morganti-Kossmann MC. CCL2 modulates cytokine production in cultured mouse astrocytes J Neuroinflammation. 2010 Oct 14;7:67.
9: Kanda H, Tateya S, Tamori Y, Kotani K, Hiasa K, Kitazawa R, Kitazawa S, Miyachi H, Maeda S, Egashira K, Kasuga M. MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity J Clin Invest. 2006 Jun;116(6):1494-505.
10: Choi DJ, Yang H, Gaire S, Lee KA, An J, Kim BG, Jou I, Park SM, Joe EH. Critical roles of astrocytic-CCL2-dependent monocyte infiltration in a DJ-1 knockout mouse model of delayed brain repair Glia. 2020 Oct;68(10):2086-2101.

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Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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