Mono-(3A-deoxy-3A-(2-carboxyethyl)thio)-altro-Sugammadex

Product Description

Mono-(3A-deoxy-3A-(2-carboxyethyl)thio)-altro-Sugammadex
Catalog number: B2027398
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 mg
Molecular Weight or Concentration: 2227
Supplied as: Chemicals
Storage: −80°C
Keywords: Mono-(3A-deoxy-3A-(2-carboxyethyl)thio)-altro-beta-cyclodextrin, Sugammadex Impurity F, Sugammadex Altro Isomer

References:
1. Bom, A., Bradley, M., Cameron, K., Clark, J. K., Van Egmond, J., Feilden, H., … & Zhang, M. Q. (2002). A novel concept of reversing neuromuscular block: Chemical encapsulation of rocuronium bromide by a cyclodextrin-based synthetic host. Angewandte Chemie International Edition, 41(2), 265-268.
2. Adam, J. M., Bennett, D. J., Breckenridge, R. J., Cameron, K. O., Clark, J. K., Donaldson, M., … & Zhang, M. Q. (2002). Cyclodextrin-derived host molecules as reversal agents for the neuromuscular blocker rocuronium bromide. Journal of Medicinal Chemistry, 45(9), 1806-1816.
3. Gijsenbergh, F., Ramael, S., Houwing, N., & van Iersel, T. (2005). First human exposure to sugammadex, a novel reversal agent for rocuronium-induced neuromuscular block. Anesthesiology, 103(4), 695-703.
4. Welliver, M. (2006). New drug administration: Sugammadex: A selective relaxant binding agent. AANA Journal, 74(5), 357-363.
5. Naguib, M. (2007). Sugammadex: Another milestone in clinical neuromuscular pharmacology. Anesthesia & Analgesia, 104(3), 575-581.
6. Nicholson, W. T., Sprung, J., & Jankowski, C. J. (2007). Sugammadex: A novel agent for the reversal of neuromuscular blockade. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 27(8), 1181-1188.
7. Suy, K., Morias, K., Cammu, G., Hans, P., van Duijnhoven, W. G., Heeringa, M., & Booij, L. H. (2007). Effective reversal of moderate rocuronium- or vecuronium-induced neuromuscular block with sugammadex, a selective relaxant binding agent. Anesthesiology, 106(2), 283-288.
8. Sacan, O., White, P. F., Tufanogullari, B., & Klein, K. (2007). Sugammadex reversal of rocuronium-induced neuromuscular block: A comparison with neostigmine–glycopyrrolate and edrophonium–atropine. Anesthesia & Analgesia, 104(3), 569-574.
9. Yang, L. P., & Keam, S. J. (2009). Sugammadex: A review of its use in anaesthetic practice. Drugs, 69(7), 919-942.
10. Chambers, D., Paulden, M., Paton, F., Heirs, M., Duffy, S., Craig, D., … & Westwood, M. (2010). Sugammadex for the reversal of muscle relaxation in general anaesthesia: A systematic review and economic evaluation. Health Technology Assessment, 14(39), 1-211.
Mono-(3A-deoxy-3A-(2-carboxyethyl)thio)-altro-Sugammadex

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