Methyl-β-cyclodextrin (Biochemistry Grade)

Description

Methyl-β-cyclodextrin
Catalog number: B2010055
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 1 g
pH: na
Supplied as: Ready-to-use
Appearance: White Powder
Applications: component of many buffers and reagents used in molecular biology and biochemistry. It has been used a a sequester of cholesterol, GPCR signal disrruption and delivery of hydrophobic drugs.
Storage: Room temperature
Keywords: β-cyclodextrin methylated, MCD
Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.

References:
1: Calcagnile M, Bettini S, Damiano F, Talà A, Tredici SM, Pagano R, Di Salvo M,
Siculella L, Fico D, De Benedetto GE, Valli L, Alifano P. Stimulatory Effects of
Methyl-β-cyclodextrin on Spiramycin Production and Physical-Chemical
Characterization of Nonhost@Guest Complexes. ACS Omega. 2018 Mar
31;3(3):2470-2478.

2: Dai S, Dulcey AE, Hu X, Wassif CA, Porter FD, Austin CP, Ory DS, Marugan J,
Zheng W. Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick
C1-deficient cells through activation of AMPK. Autophagy. 2017 Aug
3;13(8):1435-1451.

3: Piras AM, Fabiano A, Chiellini F, Zambito Y. Methyl-β-cyclodextrin quaternary
ammonium chitosan conjugate: nanoparticles vs macromolecular soluble complex.
Int J Nanomedicine. 2018 Apr 24;13:2531-2541.

4: Elamin KM, Yamashita Y, Higashi T, Motoyama K, Arima H. Supramolecular
Complex of Methyl-β-cyclodextrin with Adamantane-Grafted Hyaluronic Acid as a
Novel Antitumor Agent. Chem Pharm Bull (Tokyo). 2018 Mar 1;66(3):277-285.

5: Krutetskaya ZI, Milenina LS, Naumova AA, Butov SN, Antonov VG, Nozdrachev AD.
Methyl-β-cyclodextrin modulates thapsigargin-induced store-dependent
Ca²⁺ entry in macrophages. Dokl Biochem Biophys. 2017
Mar;473(1):88-90.

6: Trapani A, Catalano A, Carocci A, Carrieri A, Mercurio A, Rosato A,
Mandracchia D, Tripodo G, Schiavone BIP, Franchini C, Mesto E, Schingaro E,
Corbo F. Effect of Methyl-β-Cyclodextrin on the antimicrobial activity of a new
series of poorly water-soluble benzothiazoles. Carbohydr Polym. 2019 Mar
1;207:720-728.

7: Yang Q, Miyagawa M, Liu X, Zhu B, Munemasa S, Nakamura T, Murata Y, Nakamura
Y. Methyl-β-cyclodextrin potentiates the BITC-induced anti-cancer effect through
modulation of the Akt phosphorylation in human colorectal cancer cells. Biosci
Biotechnol Biochem. 2018 Dec;82(12):2158-2167.

8: De Vuyst É, Giltaire S, Lambert de Rouvroit C, Malaisse J, Mound A,
Bourtembourg M, Poumay Y, Nikkels AF, Chrétien A, Salmon M. Methyl-β-
cyclodextrin concurs with interleukin (IL)-4, IL-13 and IL-25 to induce
alterations reminiscent of atopic dermatitis in reconstructed human epidermis.
Exp Dermatol. 2018 Apr;27(4):435-437.

9: Zhang Y, Lv Y, Chen L, Wu H, Zhang Y, Suo Z, Wang S, Liang Y, Xu X, Zhou G,
Feng X. Inhibition of Epigallocatechin-3-gallate/Protein Interaction by Methyl-
β-cyclodextrin in Myofibrillar Protein Emulsion Gels under Oxidative Stress. J
Agric Food Chem. 2018 Aug 1;66(30):8094-8103.

10: Kashani K, Jalali Javaran M, Sabet MS, Moieni A. Identification of rate-
limiting enzymes involved in paclitaxel biosynthesis pathway affected by
coronatine and methyl-β-cyclodextrin in Taxus baccata L. cell suspension
cultures. Daru. 2018 Dec;26(2):129-142.

11: Shtratnikova VY, Schelkunov MI, Dovbnya DV, Bragin EY, Donova MV. Effect of
methyl-β-cyclodextrin on gene expression in microbial conversion of phytosterol.
Appl Microbiol Biotechnol. 2017 Jun;101(11):4659-4667.

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