Lyn/Syk Peptide Substrate – (5-FAM) Labeled

Product Description

Lyn/Syk Peptide Substrate – (5-FAM) Labeled
Catalog number: B2019414
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 1935.2
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: 5-FAM-EDPIYEFLPAKKK-NH2
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Zhang J, Suzuki K, Hitomi T, Siraganian RP. TOM1L1 is a Lyn substrate involved in FcepsilonRI signaling in mast cells J Biol Chem. 2007 Dec 28;282(52):37669-77.
2: Sada K, Yamamura H. Protein-tyrosine kinases and adaptor proteins in FcepsilonRI-mediated signaling in mast cells Curr Mol Med. 2003 Feb;3(1):85-94.
3: Wang J, Lin F, Wan Z, Sun X, Lu Y, Huang J, Wang F, Zeng Y, Chen YH, Shi Y, Zheng W, Li Z, Xiong C, Liu W. Profiling the origin, dynamics, and function of traction force in B cell activation Sci Signal. 2018 Aug 7;11(542):eaai9192.
4: Qin S, Chock PB. Implication of phosphatidylinositol 3-kinase membrane recruitment in hydrogen peroxide-induced activation of PI3K and Akt Biochemistry. 2003 Mar 18;42(10):2995-3003.
5: Mou DL, Wang YP, Jiang H, Xiao SY, Yu X, Li GY, Wang PZ, Sun YT, Nie QH, Huang CX, Bai XF. [Identification of a functional ITAM-like sequence within G1 cytoplasmic tail of Hantaan virus] Bing Du Xue Bao. 2007 Nov;23(6):424-8.
6: Park CH, Min SY, Yu HW, Kim K, Kim S, Lee HJ, Kim JH, Park YJ. Effects of Apigenin on RBL-2H3, RAW264.7, and HaCaT Cells: Anti-Allergic, Anti-Inflammatory, and Skin-Protective Activities Int J Mol Sci. 2020 Jun 29;21(13):4620.
7: Kanagy WK, Cleyrat C, Fazel M, Lucero SR, Bruchez MP, Lidke KA, Wilson BS, Lidke DS. Docking of Syk to FcεRI is enhanced by Lyn but limited in duration by SHIP1 Mol Biol Cell. 2022 Sep 1;33(10):ar89.
8: Yang J, Zhai Y, Huang C, Xiang Z, Liu H, Wu J, Huang Y, Liu L, Li W, Wang W, Yang J, Zhang J. RP105 Attenuates Ischemia/Reperfusion-Induced Oxidative Stress in the Myocardium via Activation of the Lyn/Syk/STAT3 Signaling Pathway Inflammation. 2024 Aug;47(4):1371-1385.
9: Lin KC, Huang DY, Huang DW, Tzeng SJ, Lin WW. Inhibition of AMPK through Lyn-Syk-Akt enhances FcεRI signal pathways for allergic response J Mol Med (Berl). 2016 Feb;94(2):183-94.
10: Tanishita Y, Sekiya H, Inohara N, Tsuchiya K, Mitsuyama M, Núñez G, Hara H. Listeria toxin promotes phosphorylation of the inflammasome adaptor ASC through Lyn and Syk to exacerbate pathogen expansion Cell Rep. 2022 Feb 22;38(8):110414.

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