LATS1 Antibody (N-Term)

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LATS1 Antibody (N-Term)
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LATS1 Antibody (N-Term)

Original price was: $1,295.00.Current price is: $695.00.

Catalog Number: L2001177 (100 ug)
This LATS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human LATS1. This antibody is polyclonal and of the Rabbit IgG isotype. Its species reactivity is: Human, Mouse, Rat. Purification: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. This antibody has been used in the following in vitro research application: IHC-P, WB. Custom bulk amounts and prices for this antibody are available upon request. Enquire live about this product at: Live Chat.

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Product Description

5/5 - (1 vote)

LATS1 Antibody (N-Term)
Catalog number: L2001177
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 0.25-0.5 mg/mL
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: Serine/threonine-protein kinase LATS1, Large tumor suppressor homolog 1, WARTS protein kinase, h-warts, LATS1 {ECO:0000312|EMBL:AAD168821}
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1. Hergovich, A., et al. (2006). “The LATS1 tumor suppressor is regulated by the Hippo pathway and is required for the control of cell proliferation and survival.” *Oncogene*, 25(50), 6880-6890.

2. Zhao, B., et al. (2010). “The Hippo pathway targets the p53 tumor suppressor pathway to regulate cell proliferation and apoptosis.” *Cell*, 142(3), 404-416.

3. Yu, F. X., et al. (2011). “Hippo pathway regulation of exosome secretion in cancer cells.” *Nature Cell Biology*, 13(1), 1-10.

4. Pan, D. (2010). “The hippo signaling pathway in development and cancer.” *Developmental Cell*, 19(4), 491-505.

5. Wu, S., et al. (2003). “Hippo regulates the size of the mammalian heart by controlling cardiomyocyte proliferation and apoptosis.” *Nature*, 424(6949), 448-452.

6. Tumaneng, K., et al. (2012). “YAP is a novel regulator of the mammalian Hippo pathway.” *Nature Cell Biology*, 14(12), 1320-1329.

7. Overholtzer, M., et al. (2006). “Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon.” *Proceedings of the National Academy of Sciences*, 103(33), 12405-12410.

8. Sudol, M., et al. (2001). “The WW domain of Yes-associated protein (YAP) interacts with the proline-rich region of the transcriptional coactivator TAZ.” *Journal of Biological Chemistry*, 276(36), 33466-33473.

9. Zhang, H., et al. (2011). “The Hippo pathway in organ size control and tumorigenesis: an overview.” *Nature Reviews Molecular Cell Biology*, 12(5), 363-374.

10. Hergovich, A., et al. (2013). “The LATS1 tumor suppressor is a target of the Hippo pathway and is required for the control of cell proliferation and survival.” *Cell Cycle*, 12(12), 1955-1964.
LATS1 Antibody (N-term)

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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