Sale!

Insulin-like Growth Factor-Binding Protein 5 (Human)

$695.00 $495.00

Catalog Number: B2010305 (10 ug)
Insulin-like Growth Factor-Binding Protein 5 (Human) is a high quality research product used as highly pure Insulin-like Growth Factor-Binding Protein 5 (Human) expressed in CHO. This protein acts as unique insulin-like growth factor-binding protein that regulates the actions of secreted insulin-like growth factors as well as stimulates osteoblast proliferation. Custom bulk orders of this product are available upon request.

In stock

SKU: B2010305 Categories: , ,

Description

Insulin-like Growth Factor-Binding Protein 5 (Human)
Catalog number: B2010305
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Insulin-like Growth Factor-Binding Protein 5 (Human) expressed in CHO. This protein acts as unique insulin-like growth factor-binding protein that regulates the actions of secreted insulin-like growth factors as well as stimulates osteoblast proliferation.
Storage: -20C
Keywords: rHuIGF-BP5; IBP-5
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Duan C, Allard JB. Insulin-Like Growth Factor Binding Protein-5 in Physiology
and Disease. Front Endocrinol (Lausanne). 2020 Mar 3;11:100.

2: Wang S, Hong Q, Geng X, Chi K, Cai G, Wu D. Insulin-Like Growth Factor
Binding Protein 5-A Probable Target of Kidney Renal Papillary Renal Cell
Carcinoma. Biomed Res Int. 2019 Nov 11;2019:3210324.

3: Yasuoka H, Garrett SM, Nguyen XX, Artlett CM, Feghali-Bostwick CA. NADPH
oxidase-mediated induction of reactive oxygen species and extracellular matrix
deposition by insulin-like growth factor binding protein-5. Am J Physiol Lung
Cell Mol Physiol. 2019 Apr 1;316(4):L644-L655.

4: Mukherjee A, Rotwein P. Insulin-like growth factor binding protein-5 in
osteogenesis: facilitator or inhibitor? Growth Horm IGF Res. 2007
Jun;17(3):179-85.

5: Beattie J, Allan GJ, Lochrie JD, Flint DJ. Insulin-like growth factor-binding
protein-5 (IGFBP-5): a critical member of the IGF axis. Biochem J. 2006 Apr
1;395(1):1-19.

6: Akkiprik M, Feng Y, Wang H, Chen K, Hu L, Sahin A, Krishnamurthy S, Ozer A,
Hao X, Zhang W. Multifunctional roles of insulin-like growth factor binding
protein 5 in breast cancer. Breast Cancer Res. 2008;10(4):212.

7: Chen Z, Zhang W, Zhang N, Zhou Y, Hu G, Xue M, Liu J, Li Y. Down-regulation
of insulin-like growth factor binding protein 5 is involved in intervertebral
disc degeneration via the ERK signalling pathway. J Cell Mol Med. 2019
Sep;23(9):6368-6377.

8: Sun M, Long J, Yi Y, Xia W. Importin α-importin β complex mediated nuclear
translocation of insulin-like growth factor binding protein-5. Endocr J. 2017
Oct 28;64(10):963-975.

9: Mohan S, Baylink DJ. Serum insulin-like growth factor binding protein
(IGFBP)-4 and IGFBP-5 levels in aging and age-associated diseases. Endocrine.
1997 Aug;7(1):87-91.
10: Bach LA. Insulin-Like Growth Factor Binding Proteins – an Update. Pediatr
Endocrinol Rev. 2015 Dec;13(2):521-30.

Products Related to Insulin-like Growth Factor-Binding Protein 5 (Human) : Proteins

Ordering Information

1- Order online using our website’s automated shopping cart and checkout system (available 24/7).

2- Order by email: info@moleculardepot.com (we accept electronic PO, available 24/7).

3- Order by Fax: 1-858-437-9884 (available 24/7).

4- Order by phone: 1-858-900-3210 (6 am – 8 pm PST).

5- Order by Text/SMS: 1-858-900-3210 (6 am – 8 pm PST).