Immunoglobulin D (IgD) from Normal Human Plasma

Product Description

Immunoglobulin D (IgD) from Normal Human Plasma
Catalog number: B2014925
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 25 ug
Molecular Weight or Concentration: 185 kDa
Supplied as: Frozen
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Immunoglobulin D (IgD), Normal Human Plasma
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Pernis B, Forni L. IgD receptors of lymphoid cells Immunol Commun. 1976;5(9):807-26.
2: Levan-Petit I, Lelievre E, Barra A, Limosin A, Gombert B, Preud’homme JL, Lecron JC. T(h)2 cytokine dependence of IgD production by normal human B cells Int Immunol. 1999 Nov;11(11):1819-28.
3: Noviski M, Zikherman J. Control of autoreactive B cells by IgM and IgD B cell receptors: maintaining a fine balance Curr Opin Immunol. 2018 Dec;55:67-74.
4: van Nieuwkoop JA, Radl J. Light chain types of IgD in human bone marrow and serum Clin Exp Immunol. 1985 Jun;60(3):654-60.
5: Dunnette SL, Gleich GJ, Weinshilboum RM. Inheritance of low serum immunoglobulin D J Clin Invest. 1978 Aug;62(2):248-55.
6: Nechvatalova J, Bartol SJW, Chovancova Z, Boon L, Vlkova M, van Zelm MC. Absence of Surface IgD Does Not Impair Naive B Cell Homeostasis or Memory B Cell Formation in IGHD Haploinsufficient Humans J Immunol. 2018 Oct 1;201(7):1928-1935.
7: Tang X, Deng Z, Ding P, Qiang W, Lu Y, Gao S, Hu Y, Yang Y, Du J, Gu C. A novel protein encoded by circHNRNPU promotes multiple myeloma progression by regulating the bone marrow microenvironment and alternative splicing J Exp Clin Cancer Res. 2022 Mar 8;41(1):85.
8: Arpin C, de Bouteiller O, Razanajaona D, Fugier-Vivier I, Brière F, Banchereau J, Lebecque S, Liu YJ. The normal counterpart of IgD myeloma cells in germinal center displays extensively mutated IgVH gene, Cmu-Cdelta switch, and lambda light chain expression J Exp Med. 1998 Apr 20;187(8):1169-78.
9: Kluin PM, Kayano H, Zani VJ, Kluin-Nelemans HC, Tucker PW, Satterwhite E, Dyer MJ. IgD class switching: identification of a novel recombination site in neoplastic and normal B cells Eur J Immunol. 1995 Dec;25(12):3504-8.
10: Spencer J, Choy M, Hussell T, Papadaki L, Kington JP, Isaacson PG. Properties of human thymic B cells Immunology. 1992 Apr;75(4):596-600.

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