Human Troponin C


Catalog Number: B2012217 (25 ug)
Human Troponin C is a high quality Human Troponin C (cTnC) purified from Human Heart. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2012217 Categories: , Tag:


Human Troponin C
Catalog number: B2012217
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 25 ug
Molecular Weight or Concentration: 18 kDa
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Tn-c, hTn-c, Troponin C type 1
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Katrukha IA. Human cardiac troponin complex. Structure and functions Biochemistry (Mosc). 2013 Dec;78(13):1447-65.
2: Rayani K, Seffernick J, Li AY, Davis JP, Spuches AM, Van Petegem F, Solaro RJ, Lindert S, Tibbits GF. Binding of calcium and magnesium to human cardiac troponin C J Biol Chem. 2021 Jan-Jun;296:100350.
3: Lopez Davila AJ, Zhu L, Fritz L, Kraft T, Chalovich JM. The Positively Charged C-Terminal Region of Human Skeletal Troponin T Retards Activation and Decreases Calcium Sensitivity Biochemistry. 2020 Nov 3;59(43):4189-4201.
4: Yan C, Sack JS. X-ray structure of a human cardiac muscle troponin_C/troponin I chimera in two crystal forms Acta Crystallogr F Struct Biol Commun. 2022 Jan 1;78(Pt 1):17-24.
5: Ovaska M, Taskinen J. A model for human cardiac troponin_C and for modulation of its Ca2+ affinity by drugs Proteins. 1991;11(2):79-94.
6: Robertson IM, Li MX, Sykes BD. Solution structure of human cardiac troponin C in complex with the green tea polyphenol, (-)-epigallocatechin 3-gallate J Biol Chem. 2009 Aug 21;284(34):23012-23.
7: Marques MA, Parvatiyar MS, Yang W, de Oliveira GAP, Pinto JR. The missing links within troponin Arch Biochem Biophys. 2019 Mar 15;663:95-100.
8: Lindhout DA, Sykes BD. Structure and dynamics of the C-domain of human cardiac troponin_C in complex with the inhibitory region of human cardiac_troponin I J Biol Chem. 2003 Jul 18;278(29):27024-34.
9: Gomes AV, Potter JD, Szczesna-Cordary D. The role of troponins in muscle contraction IUBMB Life. 2002 Dec;54(6):323-33.
10: Solaro RJ. Troponin C – troponin I interactions and molecular signalling in cardiac myofilaments Adv Exp Med Biol. 1995;382:109-15.

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