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Human Transforming Growth Factor β2

$495.00

Catalog Number: B2010334 (10 ug)
Human Transforming Growth Factor β2 is a high quality research product used as highly pure Human Transforming Growth Factor β2 expressed in HEK 293. This protein acts as a multifunctional cytokine involved in the control of cell growth and differentiation, induces fibrosis and causes the suppression of immune response. Custom bulk orders of this product are available upon request.

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SKU: B2010334 Categories: , ,

Description

Human Transforming Growth Factor β2
Catalog number: B2010334
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Human Transforming Growth Factor β2 expressed in HEK 293. This protein acts as a multifunctional cytokine involved in the control of cell growth and differentiation, induces fibrosis and causes the suppression of immune response.
Storage: -20C
Keywords: TGF-beta-2; Cetermin; G-TSF; TGFB2; Polyergin; rHuTGF-β2
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Fischer TW, Herczeg-Lisztes E, Funk W, Zillikens D, Bíró T, Paus R.
Differential effects of caffeine on hair shaft elongation, matrix and outer root
sheath keratinocyte proliferation, and transforming growth factor-β2/insulin-
like growth factor-1-mediated regulation of the hair cycle in male and female
human hair follicles in vitro. Br J Dermatol. 2014 Nov;171(5):1031-43.

2: Ojiaku CA, Chung E, Parikh V, Williams JK, Schwab A, Fuentes AL, Corpuz ML,
Lui V, Paek S, Bexiga NM, Narayan S, Nunez FJ, Ahn K, Ostrom RS, An SS,
Panettieri RA Jr. Transforming Growth Factor-β1 Decreases β2-Agonist-
induced Relaxation in Human Airway Smooth Muscle. Am J Respir Cell Mol Biol.
2019 Aug;61(2):209-218.

3: Takahashi H, Alves CRR, Stanford KI, Middelbeek RJW, Pasquale Nigro, Ryan RE,
Xue R, Sakaguchi M, Lynes MD, So K, Mul JD, Lee MY, Balan E, Pan H, Dreyfuss JM,
Hirshman MF, Azhar M, Hannukainen JC, Nuutila P, Kalliokoski KK, Nielsen S,
Pedersen BK, Kahn CR, Tseng YH, Goodyear LJ. TGF-β2 is an exercise-induced
adipokine that regulates glucose and fatty acid metabolism. Nat Metab. 2019
Feb;1(2):291-303.

4: Soma T, Tsuji Y, Hibino T. Involvement of transforming growth factor-beta2 in
catagen induction during the human hair cycle. J Invest Dermatol. 2002
Jun;118(6):993-7.

5: Stockis J, Dedobbeleer O, Lucas S. Role of GARP in the activation of latent
TGF-β1. Mol Biosyst. 2017 Sep 26;13(10):1925-1935.

6: Ganesan R, Sivalingam N. Transforming Growth Factor Beta 2 Inhibits Growth
and Proliferation Potential of Smad4 and p53 Mutated Human Colon Adenocarcinoma
Cells. Pathol Oncol Res. 2019 Apr;25(2):819-821. d

7: Su Y, Feng W, Shi J, Chen L, Huang J, Lin T. circRIP2 accelerates bladder
cancer progression via miR-1305/Tgf-β2/smad3 pathway. Mol Cancer. 2020 Feb
4;19(1):23.

8: Del Amo-Maestro L, Marino-Puertas L, Goulas T, Gomis-Rüth FX. Recombinant
production, purification, crystallization, and structure analysis of human
transforming growth factor β2 in a new conformation. Sci Rep. 2019 Jun
17;9(1):8660. 9: Matta B, Bora PS, Neuhouser AJ, Bora NS. Inhibitory role of transforming
growth factor β2 in experimental autoimmune anterior uveitis. Graefes Arch Clin
Exp Ophthalmol. 2019 May;257(5):953-960.
10: Ma J, Zhang Q, Moe MC, Zhu T. Regulation of cell-mediated collagen gel
contraction in human retinal pigment epithelium cells by vascular endothelial
growth factor compared with transforming growth factor-β2. Clin Exp Ophthalmol.
2012 Jan-Feb;40(1):e76-86.

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