Human Recombinant Citrullinated Hsp70


Catalog Number: B2012526 (100 ug)
Human Recombinant Citrullinated Hsp70 is a high quality heat shock protein 70s (Hsp70s) citrullinated. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Human Recombinant Citrullinated Hsp70
Catalog number: B2012526
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 71.7 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Heat Shock Protein 70, HspA1A, N-Terminal histidine-tagged human Hsp70 purified from E. coli, citrullinated by PAD2
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Shoda H, Fujio K, Shibuya M, Okamura T, Sumitomo S, Okamoto A, Sawada T, Yamamoto K. Detection of autoantibodies to citrullinated BiP in rheumatoid arthritis patients and pro-inflammatory role of citrullinated BiP in collagen-induced arthritis Arthritis Res Ther. 2011;13(6):R191.
2: Ge C, Weisse S, Xu B, Dobritzsch D, Viljanen J, Kihlberg J, Do NN, Schneider N, Lanig H, Holmdahl R, Burkhardt H. Key interactions in the trimolecular complex consisting of the rheumatoid arthritis-associated DRB1*04:01 molecule, the major glycosylated collagen II peptide and the T-cell receptor Ann Rheum Dis. 2022 Apr;81(4):480-489.
3: Lu MC, Lai NS, Yin WY, Yu HC, Huang HB, Tung CH, Huang KY, Yu CL. Anti-citrullinated protein antibodies activated ERK1/2 and JNK mitogen-activated protein kinases via binding to surface-expressed citrullinated GRP78 on mononuclear cells J Clin Immunol. 2013 Apr;33(3):558-66.
4: Wu X, Sun X, Sharma S, Lu Q, Yegambaram M, Hou Y, Wang T, Fineman JR, Black SM. Arginine recycling in endothelial cells is regulated BY HSP90 and the ubiquitin proteasome system Nitric Oxide. 2021 Mar 1;108:12-19.
5: Yu HC, Lai PH, Lai NS, Huang HB, Koo M, Lu MC. Increased Serum Levels of Anti-Carbamylated 78-kDa Glucose-Regulated Protein Antibody in Patients with Rheumatoid Arthritis Int J Mol Sci. 2016 Sep 8;17(9):1510.
6: Lunz W, Capettini LS, Davel AP, Munhoz CD, da Silva JF, Rossoni LV, Lemos VS, Baldo MP, Carneiro-Junior MA, Natali AJ, de Lacerda LH, Mill JG. L-NAME treatment enhances exercise-induced content of myocardial heat shock protein 72 (Hsp72) in rats Cell Physiol Biochem. 2011;27(5):479-86.
7: Chiang MC, Chen HM, Lee YH, Chang HH, Wu YC, Soong BW, Chen CM, Wu YR, Liu CS, Niu DM, Wu JY, Chen YT, Chern Y. Dysregulation of C/EBPalpha by mutant Huntingtin causes the urea cycle deficiency in Huntington’s disease Hum Mol Genet. 2007 Mar 1;16(5):483-98.
8: Fismen L, Eide T, Hjelde A, Svardal AM, Djurhuus R. Hyperoxia but not ambient pressure decreases tetrahydrobiopterin level without affecting the enzymatic capability of nitric oxide synthase in human endothelial cells Eur J Appl Physiol. 2013 Jul;113(7):1695-704.
9: Najafizadeh SR, Ghazizadeh Z, Nargesi AA, Mahdavi M, Abtahi S, Mirmiranpour H, Nakhjavani M. Analysis of serum heat shock protein 70 (HSPA1A) concentrations for diagnosis and disease activity monitoring in patients with rheumatoid arthritis Cell Stress Chaperones. 2015 May;20(3):537-43.
10: Dong W, Li X, Feng Y, Fan C, Chen Z, Zhu P. The differential expressions of 78-kDa glucose-regulated protein of infiltrating plasma cells in peripheral joints with the histopathological variants of rheumatoid synovitis Arthritis Res Ther. 2009 Jan 9;11(1):R4.

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