Human PROK2/PK2 Isoform 2 (28-78)-Amide

Description

Human PROK2/PK2 Isoform 2 (28-78)-Amide
Catalog number: B2014774
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 ug
Molecular Weight or Concentration: 5526.42
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: (Cys(ACM)3,6) PROK2 / PK2 Isoform 2 (28-78)-Amide (Human)
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Lattanzi R, Maftei D, Negri L, Fusco I, Miele R. PK2β ligand, a splice variant of prokineticin 2, is able to modulate and drive signaling through PKR1 receptor Neuropeptides. 2018 Oct;71:32-42.
2: Chen FL, Yin HY, Tang Y. PROK2-PROKR2 Signaling: New Contributor to Pleasant Touch Neurosci Bull. 2023 Feb;39(2):356-358.
3: Liu B, Qiao L, Liu K, Liu J, Piccinni-Ash TJ, Chen ZF. Molecular and neural basis of pleasant touch sensation Science. 2022 Apr 29;376(6592):483-491.
4: Balasubramanian R, Crowley WF Jr. Isolated Gonadotropin-Releasing Hormone (GnRH) Deficiency 2007 May 23 [updated 2022 May 12]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews(®) [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2023.
5: Wen Y, Zhang Z, Li Z, Liu G, Tao G, Song X, Xu Z, Shang Z, Guo T, Su Z, Chen H, You Y, Li J, Yang Z. The PROK2/PROKR2 signaling pathway is required for the migration of most olfactory bulb interneurons J Comp Neurol. 2019 Dec 15;527(18):2931-2947.
6: Wang K, Wang M, Liao X, Gao S, Hua J, Wu X, Guo Q, Xu W, Sun J, He Y, Li Q, Gao W. Locally organised and activated Fth1(hi) neutrophils aggravate inflammation of acute lung injury in an IL-10-dependent manner Nat Commun. 2022 Dec 13;13(1):7703.
7: Bao Z, Liu Y, Chen B, Miao Z, Tu Y, Li C, Chao H, Ye Y, Xu X, Sun G, Zhao P, Liu N, Liu Y, Wang X, Lam SM, Kagan VE, Bayır H, Ji J. Prokineticin-2 prevents neuronal cell deaths in a model of traumatic brain injury Nat Commun. 2021 Jul 9;12(1):4220.
8: Wu MH, Wu PR, Hsieh YH, Lin CL, Liu CJ, Ying TH. Silencing PROK2 Inhibits Invasion of Human Cervical Cancer Cells by Targeting MMP15 Expression Int J Mol Sci. 2020 Sep 2;21(17):6391.
9: Lichtenauer M, Jung C. TBX20 and the PROK2-PROKR1 pathway-new kid on the block in angiogenesis research Ann Transl Med. 2018 Nov;6(Suppl 1):S8.
10: Dodé C, Rondard P. PROK2/PROKR2 Signaling and Kallmann Syndrome Front Endocrinol (Lausanne). 2013 Apr 12;4:19.

Products Related to Human PROK2/PK2 Isoform 2 (28-78)-Amide can be found at Peptides