Human P-Selectin

Product Description

Human P-Selectin
Catalog number: B2012386
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 107 kDa
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: CD62 Antigen-like Family Member P, GMP140, Granule Membrane Protein 140, PADGEM, Platelet Activation-dependent Granule-external Membrane Protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Wagner DD. P-selectin knockout: a mouse model for various human diseases Ciba Found Symp. 1995;189:2-10; discussion 10-16, 77-8.
2: Gillies PJ, Richardson NA, Walshe J, Stephenson SA, Dawson RA, Harkin DG. Demonstration of P-selectin expression and potential function in human corneal epithelial cells Exp Eye Res. 2018 Nov;176:196-206.
3: Manwani D. P-selectin and sickle cell disease: a balancing act Blood. 2021 May 13;137(19):2573-2574.
4: González-Tajuelo R, Silván J, Pérez-Frías A, de la Fuente-Fernández M, Tejedor R, Espartero-Santos M, Vicente-Rabaneda E, Juarranz Á, Muñoz-Calleja C, Castañeda S, Gamallo C, Urzainqui A. P-Selectin preserves immune tolerance in mice and is reduced in human cutaneous lupus Sci Rep. 2017 Feb 2;7:41841.
5: Patel MS, Miranda-Nieves D, Chen J, Haller CA, Chaikof EL. Targeting P-selectin glycoprotein ligand-1/P-selectin interactions as a novel therapy for metabolic syndrome Transl Res. 2017 May;183:1-13.
6: André P. P-selectin in haemostasis Br J Haematol. 2004 Aug;126(3):298-306.
7: Liu Z, Miner JJ, Yago T, Yao L, Lupu F, Xia L, McEver RP. Differential regulation of human and murine P-selectin expression and function in vivo J Exp Med. 2010 Dec 20;207(13):2975-87.
8: Huang B, Ling Y, Lin J, Du X, Fang Y, Wu J. Force-dependent calcium signaling and its pathway of human neutrophils on P-selectin in flow Protein Cell. 2017 Feb;8(2):103-113.
9: Blann AD. Soluble P-selectin: the next step Thromb Res. 2014 Jan;133(1):3-4.
10: Neri T, Nieri D, Celi A. P-selectin blockade in COVID-19-related ARDS Am J Physiol Lung Cell Mol Physiol. 2020 Jun 1;318(6):L1237-L1238.

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