Interleukin-33 (IL-33, Human, Recombinant)


Catalog Number: B2010265 (10 ug)
Human Interleukin-33 (IL-33) is a high quality research product used as highly pure recombinant human Interleukin (expressed in E. coli). IL-33 is proinflammatory protein that is homologous (structurally and functionally) to the IL-1 cytokine family of proteins. Custom bulk orders of this product are available upon request.

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SKU: B2010265 Categories: , ,


Human Interleukin-33 (IL-33)
Catalog number: B2010265
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: n/a
Supplied as: Reconstitute before use
Appearance: Solid
Applications: highly pure recombinant human Interleukin (expressed in E. coli). IL-33 is proinflammatory protein that is homologous (structurally and functionally) to the IL-1 cytokine family of proteins.
Storage: -20C
Keywords: rHuIL-33; IL-1F11; NF-HEV; DVS 27
Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.

1: Cayrol C, Girard JP. Interleukin-33 (IL-33): A nuclear cytokine from the IL-1
family. Immunol Rev. 2018 Jan;281(1):154-168.

2: Tan Z, Liu Q, Jiang R, Lv L, Shoto SS, Maillet I, Quesniaux V, Tang J, Zhang
W, Sun B, Ryffel B. Interleukin-33 drives hepatic fibrosis through activation of
hepatic stellate cells. Cell Mol Immunol. 2018 Apr;15(4):388-398.

3: Yamamoto M, Umebashi K, Tokito A, Imamura J, Jougasaki M. Interleukin-33
induces growth-regulated oncogene-α expression and secretion in human umbilical
vein endothelial cells. Am J Physiol Regul Integr Comp Physiol. 2017 Sep

4: Huang B, Faucette AN, Pawlitz MD, Pei B, Goyert JW, Zhou JZ, El-Hage NG, Deng
J, Lin J, Yao F, Dewar RS 3rd, Jassal JS, Sandberg ML, Dai J, Cols M, Shen C,
Polin LA, Nichols RA, Jones TB, Bluth MH, Puder KS, Gonik B, Nayak NR, Puscheck
E, Wei WZ, Cerutti A, Colonna M, Chen K. Interleukin-33-induced expression of
PIBF1 by decidual B cells protects against preterm labor. Nat Med. 2017

5: Tseng CCS, Huibers MMH, van Kuik J, de Weger RA, Vink A, de Jonge N. The
Interleukin-33/ST2 Pathway Is Expressed in the Failing Human Heart and
Associated with Pro-fibrotic Remodeling of the Myocardium. J Cardiovasc Transl
Res. 2018 Feb;11(1):15-21.

6: Dalmas E, Lehmann FM, Dror E, Wueest S, Thienel C, Borsigova M, Stawiski M,
Traunecker E, Lucchini FC, Dapito DH, Kallert SM, Guigas B, Pattou F, Kerr-Conte
J, Maechler P, Girard JP, Konrad D, Wolfrum C, Böni-Schnetzler M, Finke D,
Donath MY. Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote
Insulin Secretion through Myeloid Cell Retinoic Acid Production. Immunity. 2017
Nov 21;47(5):928-942.e7.

7: Osbourn M, Soares DC, Vacca F, Cohen ES, Scott IC, Gregory WF, Smyth DJ,
Toivakka M, Kemter AM, le Bihan T, Wear M, Hoving D, Filbey KJ, Hewitson JP,
Henderson H, Gonzàlez-Cìscar A, Errington C, Vermeren S, Astier AL, Wallace WA,
Schwarze J, Ivens AC, Maizels RM, McSorley HJ. HpARI Protein Secreted by a
Helminth Parasite Suppresses Interleukin-33. Immunity. 2017 Oct

8: Stojkovic S, Kaun C, Basilio J, Rauscher S, Hell L, Krychtiuk KA, Bonstingl
C, de Martin R, Gröger M, Ay C, Holnthoner W, Eppel W, Neumayer C, Huk I, Huber
K, Demyanets S, Wojta J. Tissue factor is induced by interleukin-33 in human
endothelial cells: a new link between coagulation and inflammation. Sci Rep.
2016 May 4;6:25171.

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