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Human GABA Beta1 Receptor

Original price was: $4,595.00.Current price is: $2,295.00.

Catalog Number: B2016491 (5 mg )
Human GABA Beta1 Receptor is a high quality major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

Human GABA Beta1 Receptor
Catalog number: B2016491
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: N/A
Supplied as: N/A
Applications: a molecular tool for various biochemical applications
Storage: N/A
Keywords: Gamma-Aminobuytric Acid Type A Receptor Beta 1 Subunit, GABA(A)Receptor, Beta 1
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Zhang J, Wang H, Chen H, Li H, Xu P, Liu B, Zhang Q, Lv C, Song X. ATF3 -activated accelerating effect of LINC00941/lncIAPF on fibroblast-to-myofibroblast differentiation by blocking autophagy depending on ELAVL1/HuR in pulmonary fibrosis Autophagy. 2022 Nov;18(11):2636-2655.
2: Laverty D, Desai R, Uchański T, Masiulis S, Stec WJ, Malinauskas T, Zivanov J, Pardon E, Steyaert J, Miller KW, Aricescu AR. Cryo-EM structure of the human α1β3γ2 GABA(A) receptor in a lipid bilayer Nature. 2019 Jan;565(7740):516-520.
3: Waldvogel HJ, Faull RL. The diversity of GABA(A) receptor subunit distribution in the normal and Huntington’s disease human brain Adv Pharmacol. 2015;73:223-64.
4: Lorenz-Guertin JM, Bambino MJ, Jacob TC. γ2 GABA(A)R Trafficking and the Consequences of Human Genetic Variation Front Cell Neurosci. 2018 Aug 23;12:265.
5: Karim N, Wellendorph P, Absalom N, Johnston GA, Hanrahan JR, Chebib M. Potency of GABA at human recombinant GABA(A) receptors expressed in Xenopus oocytes: a mini review Amino Acids. 2013 Apr;44(4):1139-49.
6: Ismail FS, Faustmann PM. The potential role of astroglial GABA(A) receptors in autoimmune encephalitis associated with GABA(A) receptor antibodies and seizures Epilepsia Open. 2023 Jun;8(2):692-701.
7: Kwakowsky A, Calvo-Flores Guzmán B, Pandya M, Turner C, Waldvogel HJ, Faull RL. GABA(A) receptor subunit expression changes in the human Alzheimer’s disease hippocampus, subiculum, entorhinal cortex and superior temporal gyrus J Neurochem. 2018 Jun;145(5):374-392.
8: Rudolph U, Crestani F, Möhler H. GABA(A) receptor subtypes: dissecting their pharmacological functions Trends Pharmacol Sci. 2001 Apr;22(4):188-94.
9: Pressly B, Nguyen HM, Wulff H. GABA(A) receptor subtype selectivity of the proconvulsant rodenticide TETS Arch Toxicol. 2018 Feb;92(2):833-844.
10: Darlison MG, Pahal I, Thode C. Consequences of the evolution of the GABA(A) receptor gene family Cell Mol Neurobiol. 2005 Jun;25(3-4):607-24.

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Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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