Human CSRP2 Protein


Catalog Number: B2012053 (50 µg)
Human CSRP2 Protein is a high quality recombinant human CSRP2 protein His tagged and expressed in E.coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Human CSRP2 Protein
Catalog number: B2012053
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 µg
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: CSRP 2 protein, CSRP 2, CRP2 protein, LMO5 protein, CSRP-2 protein, CSRP-2, CSRP2, SmLIM protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Weiskirchen R, Erdel M, Utermann G, Bister K. Cloning, structural analysis, and chromosomal localization of the human CSRP2 gene encoding the LIM domain protein CRP2 Genomics. 1997 Aug 15;44(1):83-93.
2: Hoffmann C, Mao X, Brown-Clay J, Moreau F, Al Absi A, Wurzer H, Sousa B, Schmitt F, Berchem G, Janji B, Thomas C. Hypoxia promotes breast cancer cell invasion through HIF-1α-mediated up-regulation of the invadopodial actin bundling protein CSRP2 Sci Rep. 2018 Jul 5;8(1):10191.
3: Herrmann J, Borkham-Kamphorst E, Haas U, Van de Leur E, Fraga MF, Esteller M, Gressner AM, Weiskirchen R. The expression of CSRP2 encoding the LIM domain protein CRP2 is mediated by TGF-beta in smooth muscle and hepatic stellate cells Biochem Biophys Res Commun. 2006 Jul 14;345(4):1526-35.
4: Wang SJ, Wang PZ, Gale RP, Qin YZ, Liu YR, Lai YY, Jiang H, Jiang Q, Zhang XH, Jiang B, Xu LP, Huang XJ, Liu KY, Ruan GR. Cysteine and glycine-rich protein 2 (CSRP2) transcript levels correlate with leukemia relapse and leukemia-free survival in adults with B-cell acute lymphoblastic leukemia and normal cytogenetics Oncotarget. 2017 May 30;8(22):35984-36000.
5: Chen L, Long X, Duan S, Liu X, Chen J, Lan J, Liu X, Huang W, Geng J, Zhou J. CSRP2 suppresses colorectal cancer progression via p130Cas/Rac1 axis-meditated ERK, PAK, and HIPPO signaling pathways Theranostics. 2020 Sep 2;10(24):11063-11079.
6: Guru A, Lite C, Freddy AJ, Issac PK, Pasupuleti M, Saraswathi NT, Arasu MV, Al-Dhabi NA, Arshad A, Arockiaraj J. Intracellular ROS scavenging and antioxidant regulation of WL15 from cysteine and glycine-rich protein 2 demonstrated in zebrafish in vivo model Dev Comp Immunol. 2021 Jan;114:103863.
7: Günther K, Stoll D, Jakse G, Gressner AM, Weiskirchen R. Rapid detection of CSRP2 mRNA in mouse, rat, and human using LightCycler-based quantitative real-time polymerase chain reaction Anal Biochem. 2003 Mar 1;314(1):144-8.
8: Chen CH, Ho HH, Jiang WC, Ao-Ieong WS, Wang J, Orekhov AN, Sobenin IA, Layne MD, Yet SF. Cysteine-rich protein 2 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation in mice J Biomed Sci. 2022 Apr 12;29(1):25.
9: Wang J, Guan X, Zhang Y, Ge S, Zhang L, Li H, Wang X, Liu R, Ning T, Deng T, Zhang H, Jiang X, Ba Y, Huang D. Exosomal miR-27a Derived from Gastric Cancer Cells Regulates the Transformation of Fibroblasts into Cancer-Associated Fibroblasts Cell Physiol Biochem. 2018;49(3):869-883.
10: Weiskirchen R, Moser M, Weiskirchen S, Erdel M, Dahmen S, Buettner R, Gressner AM. LIM-domain protein cysteine- and glycine-rich protein 2 (CRP2) is a novel marker of hepatic stellate cells and binding partner of the protein inhibitor of activated STAT1 Biochem J. 2001 Nov 1;359(Pt 3):485-96.

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Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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