Human CRYGN Protein


Catalog Number: B2012039 (100 µg)
Human CRYGN Protein is a high quality recombinant human CRYGN protein His tagged and expressed in E.coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2012039 Categories: , Tag:


Human CRYGN Protein
Catalog number: B2012039
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 1 mg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: gamma N protein, gamma-crystallin N protein, Crystallin protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Bawankar M, Thakur AK. Mechanism of human γD-crystallin protein aggregation in UV-C light Mol Vis. 2021 Jul 1;27:415-428. eCollection 2021.
2: Roshan M, Vijaya PH, Lavanya GR, Shama PK, Santhiya ST, Graw J, Gopinath PM, Satyamoorthy K. A novel human CRYGD mutation in a juvenile autosomal dominant cataract Mol Vis. 2010 May 22;16:887-96.
3: de Figueirêdo ES, Giordano GG, Tavares A, da Silva MJ, de Vasconcellos JP, Arieta CE, de Melo MB. Novel human CRYGD rare variant in a Brazilian family with congenital cataract Mol Vis. 2011;17:2207-11. Epub 2011 Aug 16.
4: Strofaldi A, Khan AR, McManus JJ. Surface Exposed Free Cysteine Suppresses Crystallization of Human γD-Crystallin J Mol Biol. 2021 Nov 5;433(22):167252.
5: Plotnikova OV, Kondrashov FA, Vlasov PK, Grigorenko AP, Ginter EK, Rogaev EI. Conversion and compensatory evolution of the gamma-crystallin genes and identification of a cataractogenic mutation that reverses the sequence of the human CRYGD gene to an ancestral state Am J Hum Genet. 2007 Jul;81(1):32-43.
6: Smith RS, Hawes NL, Chang B, Roderick TH, Akeson EC, Heckenlively JR, Gong X, Wang X, Davisson MT. Lop12, a mutation in mouse Crygd causing lens opacity similar to human Coppock cataract Genomics. 2000 Feb 1;63(3):314-20.
7: Lyu D, Zhang L, Qin Z, Ni S, Li J, Lu B, Hao S, Tang Q, Yin H, Chen Z, Yan YB, Ji J, He J, Nagy A, Fu Q, Yao K. Modeling congenital cataract in vitro using patient-specific induced pluripotent stem cells NPJ Regen Med. 2021 Oct 1;6(1):60.
8: Lin M, Jin Y, Chen X, Sui Y, Li Y, Li H, Ni X, Zhao N, Lu Y, Jiang M. Increased hydrophobicity of CRYGD p.(Ala159ProfsTer9): Suspected cause of congenital cataracts in a large Chinese family Mol Genet Genomic Med. 2020 Oct;8(10):e1436.
9: Zhuang X, Wang L, Song Z, Xiao W. A Novel Insertion Variant of CRYGD Is Associated with Congenital Nuclear Cataract in a Chinese Family PLoS One. 2015 Jul 6;10(7):e0131471.
10: Serebryany E, Yu S, Trauger SA, Budnik B, Shakhnovich EI. Dynamic disulfide exchange in a crystallin protein in the human eye lens promotes cataract-associated aggregation J Biol Chem. 2018 Nov 16;293(46):17997-18009.

Products Related to Human CRYGN Protein can be found at Proteins

Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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