Human CRTAP Protein


Catalog Number: B2012034 (20 µg)
Human CRTAP Protein is a high quality recombinant human CRTAP protein His tagged and expressed in E.coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2012034 Categories: , Tag:


Human CRTAP Protein
Catalog number: B2012034
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 20 µg
Molecular Weight or Concentration: 500 µg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: Cartilage-associated protein precursor protein, CASP protein, LEPREL3 protein, OI7 protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Van Dijk FS, Sillence DO. Osteogenesis imperfecta: clinical diagnosis, nomenclature and severity assessment Am J Med Genet A. 2014 Jun;164A(6):1470-81.
2: Morello R, Rauch F. Role of cartilage-associated protein in skeletal development Curr Osteoporos Rep. 2010 Jun;8(2):77-83.
3: Tonachini L, Morello R, Monticone M, Skaug J, Scherer SW, Cancedda R, Castagnola P. cDNA cloning, characterization and chromosome mapping of the gene encoding human cartilage associated protein (CRTAP) Cytogenet Cell Genet. 1999;87(3-4):191-4.
4: Xu H, Lenhart SA, Chu EY, Chavez MB, Wimer HF, Dimori M, Somerman MJ, Morello R, Foster BL, Hatch NE. Dental and craniofacial defects in the Crtap(-/-) mouse model of osteogenesis imperfecta type VII Dev Dyn. 2020 Jul;249(7):884-897.
5: Grol MW, Haelterman NA, Lim J, Munivez EM, Archer M, Hudson DM, Tufa SF, Keene DR, Lei K, Park D, Kuzawa CD, Ambrose CG, Eyre DR, Lee BH. Tendon and motor phenotypes in the Crtap(-/-) mouse model of recessive osteogenesis imperfecta Elife. 2021 May 26;10:e63488.
6: Martin E, Shapiro JR. Osteogenesis imperfecta:epidemiology and pathophysiology Curr Osteoporos Rep. 2007 Sep;5(3):91-7.
7: Valli M, Barnes AM, Gallanti A, Cabral WA, Viglio S, Weis MA, Makareeva E, Eyre D, Leikin S, Antoniazzi F, Marini JC, Mottes M. Deficiency of CRTAP in non-lethal recessive osteogenesis imperfecta reduces collagen deposition into matrix Clin Genet. 2012 Nov;82(5):453-9.
8: Marini JC, Cabral WA, Barnes AM, Chang W. Components of the collagen prolyl 3-hydroxylation complex are crucial for normal bone development Cell Cycle. 2007 Jul 15;6(14):1675-81.
9: Chang W, Barnes AM, Cabral WA, Bodurtha JN, Marini JC. Prolyl 3-hydroxylase 1 and CRTAP are mutually stabilizing in the endoplasmic reticulum collagen prolyl 3-hydroxylation complex Hum Mol Genet. 2010 Jan 15;19(2):223-34.
10: Marini JC, Cabral WA, Barnes AM. Null mutations in LEPRE1 and CRTAP cause severe recessive osteogenesis imperfecta Cell Tissue Res. 2010 Jan;339(1):59-70.

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Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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