Human COPZ1 Protein

Description

Human COPZ1 Protein
Catalog number: B2012009
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 µg
Molecular Weight or Concentration: 1 mg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: COPZ1, COPZ protein, zeta1-COP protein, Coatomer protein complex protein, COPZ 1 protein, CGI-120 protein, COPZ-1, COPZ-1 protein, subunit zeta1 protein, COPZ 1
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Zhang Y, Kong Y, Ma Y, Ni S, Wikerholmen T, Xi K, Zhao F, Zhao Z, Wang J, Huang B, Chen A, Yao Z, Han M, Feng Z, Hu Y, Thorsen F, Wang J, Li X. Loss of COPZ1 induces NCOA4 mediated autophagy and ferroptosis in glioblastoma cell lines Oncogene. 2021 Feb;40(8):1425-1439.
2: Sui B, Wang M, Cheng C, Zhang Q, Zhang J, Fan D, Xu P. Nanogel-facilitated Protein Intracellular Specific Degradation through Trim-Away Adv Funct Mater. 2021 Jul 23;31(30):2010556.
3: Di Marco T, Bianchi F, Sfondrini L, Todoerti K, Bongarzone I, Maffioli EM, Tedeschi G, Mazzoni M, Pagliardini S, Pellegrini S, Neri A, Anania MC, Greco A. COPZ1 depletion in thyroid tumor cells triggers type I IFN response and immunogenic cell death Cancer Lett. 2020 Apr 28;476:106-119.
4: Anania MC, Cetti E, Lecis D, Todoerti K, Gulino A, Mauro G, Di Marco T, Cleris L, Pagliardini S, Manenti G, Belmonte B, Tripodo C, Neri A, Greco A. Targeting COPZ1 non-oncogene addiction counteracts the viability of thyroid tumor cells Cancer Lett. 2017 Dec 1;410:201-211.
5: Shtutman M, Baig M, Levina E, Hurteau G, Lim CU, Broude E, Nikiforov M, Harkins TT, Carmack CS, Ding Y, Wieland F, Buttyan R, Roninson IB. Tumor-specific silencing of COPZ2 gene encoding coatomer protein complex subunit ζ 2 renders tumor cells dependent on its paralogous gene COPZ1 Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12449-54.
6: Novoa-Aponte L, Ramírez D, Argüello JM. The interplay of the metallosensor CueR with two distinct CopZ chaperones defines copper homeostasis in Pseudomonas aeruginosa J Biol Chem. 2019 Mar 29;294(13):4934-4945.
7: Teramoto H, Yukawa H, Inui M. Copper homeostasis-related genes in three separate transcriptional units regulated by CsoR in Corynebacterium glutamicum Appl Microbiol Biotechnol. 2015 Apr;99(8):3505-17.
8: Bensellam M, Maxwell EL, Chan JY, Luzuriaga J, West PK, Jonas JC, Gunton JE, Laybutt DR. Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells Diabetologia. 2016 Jul;59(7):1492-1502.
9: Chen S, Li H, Chen S, Wang B, Zhang K. BMI1 promotes the proliferation and inhibits autophagy of breast cancer cells by activating COPZ1 Clin Transl Oncol. 2022 Jul 4.
10: Chi Q, Geng X, Xu K, Wang C, Zhao H. Potential targets and molecular mechanism of miR-331-3p in hepatocellular carcinoma identified by weighted gene coexpression network analysis Biosci Rep. 2020 Jun 26;40(6):BSR20200124.

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