Human CIB2 Protein (High Purity)


Catalog Number: B2011957 (100 µg)
Human CIB2 Protein is a high quality recombinant human CIB2 protein His tagged and expressed in E.coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

In stock

SKU: B2011957 Categories: , Tag:


Human CIB2 Protein
Catalog number: B2011957
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 0.5 mg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: calcium and integrin binding family member 2 protein, CIB-2, CIB-2 protein, KIP2, CIB 2 protein, CIB 2, CIB2
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Sethna S, Scott PA, Giese APJ, Duncan T, Jian X, Riazuddin S, Randazzo PA, Redmond TM, Bernstein SL, Riazuddin S, Ahmed ZM. CIB2 regulates mTORC1 signaling and is essential for autophagy and visual function Nat Commun. 2021 Jun 23;12(1):3906.
2: Liang X, Qiu X, Dionne G, Cunningham CL, Pucak ML, Peng G, Kim YH, Lauer A, Shapiro L, Müller U. CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells Neuron. 2021 Jul 7;109(13):2131-2149.e15.
3: Dal Cortivo G, Marino V, Iacobucci C, Vallone R, Arlt C, Rehkamp A, Sinz A, Dell’Orco D. Oligomeric state, hydrodynamic properties and target recognition of human Calcium and Integrin Binding protein 2 (CIB2) Sci Rep. 2019 Oct 21;9(1):15058.
4: Holt JR, Tobin M, Elferich J, Gouaux E, Ballesteros A, Yan Z, Ahmed ZM, Nicolson T. Putting the Pieces Together: the Hair Cell Transduction Complex J Assoc Res Otolaryngol. 2021 Dec;22(6):601-608.
5: Dal Cortivo G, Dell’Orco D. Calcium- and Integrin-Binding Protein 2 (CIB2) in Physiology and Disease: Bright and Dark Sides Int J Mol Sci. 2022 Mar 24;23(7):3552.
6: Jacoszek A, Pollak A, Płoski R, Ołdak M. Advances in genetic hearing loss: CIB2 gene Eur Arch Otorhinolaryngol. 2017 Apr;274(4):1791-1795.
7: Riazuddin S, Belyantseva IA, Giese AP, Lee K, Indzhykulian AA, Nandamuri SP, Yousaf R, Sinha GP, Lee S, Terrell D, Hegde RS, Ali RA, Anwar S, Andrade-Elizondo PB, Sirmaci A, Parise LV, Basit S, Wali A, Ayub M, Ansar M, Ahmad W, Khan SN, Akram J, Tekin M, Riazuddin S, Cook T, Buschbeck EK, Frolenkov GI, Leal SM, Friedman TB, Ahmed ZM. Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48 Nat Genet. 2012 Nov;44(11):1265-71.
8: Patel K, Giese AP, Grossheim JM, Hegde RS, Delio M, Samanich J, Riazuddin S, Frolenkov GI, Cai J, Ahmed ZM, Morrow BE. A Novel C-Terminal CIB2 (Calcium and Integrin Binding Protein 2) Mutation Associated with Non-Syndromic Hearing Loss in a Hispanic Family PLoS One. 2015 Oct 1;10(10):e0133082.
9: Koenekoop RK, Arriaga MA, Trzupek KM, Lentz JJ. Usher Syndrome Type I 1999 Dec 10 [updated 2020 Oct 8]. In: Adam MP, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews(®) [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2022.
10: Booth KT, Kahrizi K, Babanejad M, Daghagh H, Bademci G, Arzhangi S, Zareabdollahi D, Duman D, El-Amraoui A, Tekin M, Najmabadi H, Azaiez H, Smith RJ. Variants in CIB2 cause DFNB48 and not USH1J Clin Genet. 2018 Apr;93(4):812-821.

Products Related to Human CIB2 Protein can be found at Proteins

How to Order

1- Order online using our website’s automated shopping cart and checkout system (available 24/7).

2- Order by email: (we accept electronic PO, available 24/7).

3- Order by Fax: 1-858-437-9884 (available 24/7).

4- Order by phone: 1-858-900-3210 (6 am – 8 pm PST).

5- Order by Text/SMS: 1-858-900-3210 (6 am – 8 pm PST).