Human CIB1 Protein


Catalog Number: B2012405 (25 ug)
Human CIB1 Protein is a high quality human Calcium and Integrin-binding Protein 1 expressed in E. coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2012405 Categories: , Tag:


Human CIB1 Protein
Catalog number: B2012405
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 25 ug
Molecular Weight or Concentration: 23 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Calcium and integrin-binding protein 1, Calmyrin, DNA-PKcs-interacting protein, Kinase-interacting protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Blackford AN, Jackson SP. ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response Mol Cell. 2017 Jun 15;66(6):801-817.
2: Leisner TM, Freeman TC, Black JL, Parise LV. CIB1: a small protein with big ambitions FASEB J. 2016 Aug;30(8):2640-50.
3: de Jong SJ, Créquer A, Matos I, Hum D, Gunasekharan V, Lorenzo L, Jabot-Hanin F, Imahorn E, Arias AA, Vahidnezhad H, Youssefian L, Markle JG, Patin E, D’Amico A, Wang CQF, Full F, Ensser A, Leisner TM, Parise LV, Bouaziz M, Maya NP, Cadena XR, Saka B, Saeidian AH, Aghazadeh N, Zeinali S, Itin P, Krueger JG, Laimins L, Abel L, Fuchs E, Uitto J, Franco JL, Burger B, Orth G, Jouanguy E, Casanova JL. The human CIB1-EVER1-EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses J Exp Med. 2018 Sep 3;215(9):2289-2310.
4: Wang X, Peng X, Zhang X, Xu H, Lu C, Liu L, Song J, Zhang Y. The Emerging Roles of CIB1 in Cancer Cell Physiol Biochem. 2017;43(4):1413-1424.
5: Hui L, Wang F. Research Advances of Calcium-and Integrin-binding Protein 1 in Tumors Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2017 Oct 30;39(5):721-726.
6: Yim N, Ryu SW, Choi K, Lee KR, Lee S, Choi H, Kim J, Shaker MR, Sun W, Park JH, Kim D, Heo WD, Choi C. Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein-protein interaction module Nat Commun. 2016 Jul 22;7:12277.
7: Wu CJ, Li X, Sommers CL, Kurima K, Huh S, Bugos G, Dong L, Li W, Griffith AJ, Samelson LE. Expression of a TMC6-TMC8-CIB1 heterotrimeric complex in lymphocytes is regulated by each of the components J Biol Chem. 2020 Nov 20;295(47):16086-16099.
8: Mühlhäuser WW, Hörner M, Weber W, Radziwill G. Light-Regulated Protein Kinases Based on the CRY2-CIB1 System Methods Mol Biol. 2017;1596:257-270.
9: Liu Y, Zhou Y, Zhang P, Li X, Duan C, Zhang C. CHIP-mediated CIB1 ubiquitination regulated epithelial-mesenchymal transition and tumor metastasis in lung adenocarcinoma Cell Death Differ. 2021 Mar;28(3):1026-1040.
10: White C, Yang J, Monteiro MJ, Foskett JK. CIB1, a ubiquitously expressed Ca2+-binding protein ligand of the InsP3 receptor Ca2+ release channel J Biol Chem. 2006 Jul 28;281(30):20825-20833.

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