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Human CARD18 Protein

$895.00

Catalog Number: B2011695 (50 µg)
Human CARD18 Protein is a high quality recombinant human CARD18 protein His tagged and expressed in E. coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2011695 Categories: ,

Description

Human CARD18 Protein
Catalog number: B2011695
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 µg
Molecular Weight or Concentration: 500 µg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: pseudo-ICE protein, CARD-18, Caspase recruitment domain-containing protein 18 protein, ICEBERG protein, CARD18, CARD 18, CARD-18 protein, UNQ5804 protein, CARD 18 protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Aral K, Berdeli E, Cooper PR, Milward MR, Kapila Y, Karadede Ünal B, Aral CA, Berdeli A. Differential expression of inflammasome regulatory transcripts in periodontal disease J Periodontol. 2020 May;91(5):606-616.
2: Qin H, Jin J, Fischer H, Mildner M, Gschwandtner M, Mlitz V, Eckhart L, Tschachler E. The caspase-1 inhibitor CARD18 is specifically expressed during late differentiation of keratinocytes and its expression is lost in lichen planus J Dermatol Sci. 2017 Aug;87(2):176-182.
3: Lu A, Li Y, Schmidt FI, Yin Q, Chen S, Fu TM, Tong AB, Ploegh HL, Mao Y, Wu H. Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism Nat Struct Mol Biol. 2016 May;23(5):416-25.
4: Göblös A, Danis J, Vas K, Bata-Csörgő Z, Kemény L, Széll M. Keratinocytes express functional CARD18, a negative regulator of inflammasome activation, and its altered expression in psoriasis may contribute to disease pathogenesis Mol Immunol. 2016 May;73:10-8.
5: Green DR, Melino G. ICE heats up Cell Death Differ. 2001 Jun;8(6):549-50.
6: Mahakur S, Saikia B, Minz M, Minz RW, Nada R, Anand S, Sharma A, Jha V, Joshi N, Goel L, Arora A, Joshi K. Allo-specific immune response profiles indicative of acute rejection in kidney allografts using an in vitro lymphocyte culture-based model Clin Exp Nephrol. 2018 Apr;22(2):465-473.
7: Tan C, Liu S, Xiang Z. [The expression of CARD18 in apoptin-transfected gastric cancer cells and gastric adenocarcinoma tissues] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2013 Aug;29(8):858-61.
8: Wright CM, Savarimuthu Francis SM, Tan ME, Martins MU, Winterford C, Davidson MR, Duhig EE, Clarke BE, Hayward NK, Yang IA, Bowman RV, Fong KM. MS4A1 dysregulation in asbestos-related lung squamous cell carcinoma is due to CD20 stromal lymphocyte expression PLoS One. 2012;7(4):e34943.
9: Johansson Å, Eriksson N, Becker RC, Storey RF, Himmelmann A, Hagström E, Varenhorst C, Axelsson T, Barratt BJ, James SK, Katus HA, Steg PG, Syvänen AC, Wallentin L, Siegbahn A; PLATO Investigators. NLRC4 Inflammasome Is an Important Regulator of Interleukin-18 Levels in Patients With Acute Coronary Syndromes: Genome-Wide Association Study in the PLATelet inhibition and patient Outcomes Trial (PLATO) Circ Cardiovasc Genet. 2015 Jun;8(3):498-506.
10: da Cunha JP, Galante PA, de Souza SJ. Different evolutionary strategies for the origin of caspase-1 inhibitors J Mol Evol. 2008 Jun;66(6):591-7.

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