Human Carbonic Anhydrase 2


Catalog Number: B2012381 (20 ug)
Human Carbonic Anhydrase 2 is a high quality Human Carbonic Anhydrase 2 expressed in E. coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Human Carbonic Anhydrase 2
Catalog number: B2012381
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 20 ug
Molecular Weight or Concentration: 29.2 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Carbonic anhydrase 2, Carbonate dehydratase 2, Carbonic Anhydrase II, CA-II, Carbonic anhydrase C
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Su H, Hu K, Liu Z, Chen K, Xu J. Carbonic anhydrase 2 and 3 as risk biomarkers for dilated cardiomyopathy associated heart failure Ann Palliat Med. 2021 Dec;10(12):12554-12565.
2: Zhang C, Wang H, Chen Z, Zhuang L, Xu L, Ning Z, Zhu Z, Wang P, Meng Z. Carbonic anhydrase 2 inhibits epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma Carcinogenesis. 2018 Apr 5;39(4):562-570.
3: Berrino E, Angeli A, Zhdanov DD, Kiryukhina AP, Milaneschi A, De Luca A, Bozdag M, Carradori S, Selleri S, Bartolucci G, Peat TS, Ferraroni M, Supuran CT, Carta F. Azidothymidine “Clicked” into 1,2,3-Triazoles: First Report on Carbonic Anhydrase-Telomerase Dual-Hybrid Inhibitors J Med Chem. 2020 Jul 9;63(13):7392-7409.
4: Kocyigit UM, Taslimi P, Gezegen H, Gulçin İ, Ceylan M. Evaluation of acetylcholinesterase and carbonic anhydrase inhibition profiles of 1,2,3,4,6-pentasubstituted-4-hydroxy-cyclohexanes J Biochem Mol Toxicol. 2017 Sep;31(9).
5: Annan DA, Maishi N, Soga T, Dawood R, Li C, Kikuchi H, Hojo T, Morimoto M, Kitamura T, Alam MT, Minowa K, Shinohara N, Nam JM, Hida Y, Hida K. Carbonic anhydrase 2 (CAII) supports tumor blood endothelial cell survival under lactic acidosis in the tumor microenvironment Cell Commun Signal. 2019 Dec 17;17(1):169.
6: Gul HI, Kucukoglu K, Yamali C, Bilginer S, Yuca H, Ozturk I, Taslimi P, Gulcin I, Supuran CT. Synthesis of 4-(2-substituted hydrazinyl)benzenesulfonamides and their carbonic anhydrase inhibitory effects J Enzyme Inhib Med Chem. 2016 Aug;31(4):568-73.
7: Kalinin S, Kovalenko A, Valtari A, Nocentini A, Gureev M, Urtti A, Korsakov M, Supuran CT, Krasavin M. 5-(Sulfamoyl)thien-2-yl 1,3-oxazole inhibitors of carbonic anhydrase II with hydrophilic periphery J Enzyme Inhib Med Chem. 2022 Dec;37(1):1005-1011.
8: Kennedy CR, Goya Grocin A, Kovačič T, Singh R, Ward JA, Shenoy AR, Tate EW. A Probe for NLRP3 Inflammasome Inhibitor MCC950 Identifies Carbonic Anhydrase 2 as a Novel Target ACS Chem Biol. 2021 Jun 18;16(6):982-990.
9: Ip YK, Koh CZY, Hiong KC, Choo CYL, Boo MV, Wong WP, Neo ML, Chew SF. Carbonic anhydrase 2-like in the giant clam, Tridacna squamosa: characterization, localization, response to light, and possible role in the transport of inorganic carbon from the host to its symbionts Physiol Rep. 2017 Dec;5(23):e13494.
10: Xuan GS, Zhan JH, Zhang AM, Li W, Zheng K. Inhibition of carbonic anhydrase II by sulfonamide derivatives Pharmazie. 2021 Sep 1;76(9):412-415.

Products Related to Human Carbonic Anhydrase 2 can be found at Enzymes

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