Human C1 Esterase Inhibitor Depleted Plasma


Catalog Number: B2012624 (5 mL)
Human C1 Esterase Inhibitor Depleted Plasma is a high quality human plasma depleted of C1 Esterase. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Human C1 Esterase Inhibitor Depleted Plasma
Catalog number: B2012624
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mL
Molecular Weight or Concentration: <0.01 IU/ml
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Human C1 Inhibitor Depleted Plasma
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Simon TL, Kalina U, Laske R, Mycroft S, Widmer E, Roth NJ. Manufacturing of plasma-derived C1-inhibitor concentrate for treatment of patients with hereditary angioedema Allergy Asthma Proc. 2020 Mar 1;41(2):99-107.
2: Kaplan AP, Joseph K. Complement, Kinins, and Hereditary Angioedema: Mechanisms of Plasma Instability when C1 Inhibitor is Absent Clin Rev Allergy Immunol. 2016 Oct;51(2):207-15.
3: Keizer MP, Kamp AM, Brouwer N, van de Wetering MD, Wouters D, Kuijpers TW. Plasma-derived mannose-binding lectin shows a direct interaction with C1-inhibitor Mol Immunol. 2014 Apr;58(2):187-93.
4: Wiman B, Nilsson T. A new simple method for determination of C1-esterase inhibitor activity in plasma Clin Chim Acta. 1983 Mar 14;128(2-3):359-66.
5: Davis AE 3rd. The pathophysiology of hereditary angioedema Clin Immunol. 2005 Jan;114(1):3-9.
6: Zhou ZH, Chen T, Arora K, Hyams K, Kozlowski S. Complement C1 esterase inhibitor levels linked to infections and contaminated heparin-associated adverse events PLoS One. 2012;7(4):e34978.
7: Mossberg M, Ståhl AL, Kahn R, Kristoffersson AC, Tati R, Heijl C, Segelmark M, Leeb-Lundberg LMF, Karpman D. C1-Inhibitor Decreases the Release of Vasculitis-Like Chemotactic Endothelial Microvesicles J Am Soc Nephrol. 2017 Aug;28(8):2472-2481.
8: Pannell R, Kung W, Gurewich V. C1-inhibitor prevents non-specific plasminogen activation by a prourokinase mutant without impeding fibrin-specific fibrinolysis J Thromb Haemost. 2007 May;5(5):1047-54.
9: van der Graaf F, Koedam JA, Bouma BN. Inactivation of kallikrein in human plasma J Clin Invest. 1983 Jan;71(1):149-58.
10: Lai Y, Zhang G, Inhaber N, Bernstein JA, Cwik M, Zhou Z, Chockalingam PS, Wu J. A robust multiplexed assay to quantify C1-inhibitor, C1q, and C4 proteins for in vitro diagnosis of hereditary angioedema from dried blood spot J Pharm Biomed Anal. 2021 Feb 20;195:113844.

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