High Rheumatoid Factor Positive Serum


Catalog Number: B2010861 (1 mL)
High Rheumatoid Factor Positive Serum is human serum containing extremely high levels of Rheumatoid Factor antibodies (RF), ranging from 2500 IU/mL to over 25,000 IU/mL. This product has been used as molecular tool to study the interference of Rheumatoid Factor in immunoassays. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

SKU: B2010861 Categories: , Tag:


High Rheumatoid Factor Positive Serum
Catalog number: B2010861
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mL
Molecular Weight or Concentration: na
Supplied as: Human serum
Applications: molecular tool for various interference studies
Storage: -20°C
Keywords: high RF, RF > 2500 IU/mL, high RF serum
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Rao DA, Gurish MF, Marshall JL, Slowikowski K, Fonseka CY, Liu Y, Donlin LT, Henderson LA, Wei K, Mizoguchi F, Teslovich NC, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, Lee YC, Todd DJ, Bykerk VP, Goodman SM, Pernis AB, Ivashkiv LB, Karlson EW, Nigrovic PA, Filer A, Buckley CD, Lederer JA, Raychaudhuri S, Brenner MB. Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis Nature. 2017 Feb 1;542(7639):110-114.
2: Shi L, Hu F, Xu C, Zhu H, Qie D, Yuan C, Tao Y, Liu H. Plasma exchange successfully treated macrophage activation syndrome in rheumatoid factor-positive polyarticular juvenile idiopathic arthritis with co-existing pneumonia Int J Rheum Dis. 2018 May;21(5):1142-1145.
3: Bartlett DB, Willis LH, Slentz CA, Hoselton A, Kelly L, Huebner JL, Kraus VB, Moss J, Muehlbauer MJ, Spielmann G, Kraus WE, Lord JM, Huffman KM. Ten weeks of high-intensity interval walk training is associated with reduced disease activity and improved innate immune function in older adults with rheumatoid arthritis: a pilot study Arthritis Res Ther. 2018 Jun 14;20(1):127.
4: Fan W, Xu L, Xie L, Yang D, Liu X, Zhang J, Li Y, Yi C. Negative interference by rheumatoid factor of plasma B-type natriuretic peptide in chemiluminescent microparticle immunoassays PLoS One. 2014 Aug 21;9(8):e105304.
5: Taghadosi M, Samimi Z, Assar S, Salahshoor MR, Jalili C. Plasma Leptin Does Not Reflect the Effect of High Body Mass Index on Disease Activity in Rheumatoid Arthritis Immunol Invest. 2020 Feb;49(1-2):32-45.
6: Abildtrup M, Kingsley GH, Scott DL. Calprotectin as a biomarker for rheumatoid arthritis: a systematic review J Rheumatol. 2015 May;42(5):760-70.
7: Hughes-Austin JM, Deane KD, Giles JT, Derber LA, Zerbe GO, Dabelea DM, Sokolove J, Robinson WH, Holers VM, Norris JM. Plasma adiponectin levels are associated with circulating inflammatory cytokines in autoantibody positive first-degree relatives of rheumatoid arthritis patients PLoS One. 2018 Jun 25;13(6):e0199578.
8: Rantapää-Dahlqvist S, Boman K, Tarkowski A, Hallmans G. Up regulation of monocyte chemoattractant protein-1 expression in anti-citrulline antibody and immunoglobulin M rheumatoid factor positive subjects precedes onset of inflammatory response and development of overt rheumatoid arthritis Ann Rheum Dis. 2007 Jan;66(1):121-3.
9: Lovece S, Stern R, Kagen LJ. Effects of rheumatoid factor, antinuclear antibodies and plasma reagin on the serologic assay for Lyme disease J Rheumatol. 1991 Dec;18(12):1813-8.
10: Twomey JJ, Rossen RD, Lewis VM, Morgan AC, McCormick KJ. Rheumatoid factor positive plasma and humoral cytotoxicity to malignant melanoma Cancer. 1978 Apr;41(4):1307-12.

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Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

2,500-4,999 IU/mL, 5,000-7,499 IU/mL, 7,500-9,999 IU/mL, 10,000- 14,999 IU/mL, 15,000-19,999 IU/mL, 20,000-24,999 IU/mL, > 25,000 IU/mL

How to Order

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2- Order by email: (we accept electronic PO, available 24/7).

3- Order by Fax: 1-858-437-9884 (available 24/7).

4- Order by phone: 1-858-900-3210 (6 am – 8 pm PST).

5- Order by Text/SMS: 1-858-900-3210 (6 am – 8 pm PST).