Heptakis(6-deoxy-6-chloro)-gamma-cyclodextrin
Original price was: $1,795.00.$895.00Current price is: $895.00.
Catalog Number: B2027400 (100 mg)
Heptakis(6-deoxy-6-chloro)-gamma-cyclodextrin is a halogenated cyclic oligosaccharide derivative featuring a central hydrophobic cavity with primary C-6 position hydroxyl groups selectively substituted by chlorine atoms. The introduction of chloro functional groups alters the steric profile and cavity polarity, modifying host-guest binding affinities and structural reactivity compared to native cyclodextrins. This chemical derivative serves as a versatile intermediate and host molecule in supramolecular chemistry and the synthesis of specialized functional materials. Custom bulk amounts of this product are available upon request.
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Product Description
Heptakis(6-deoxy-6-chloro)-gamma-cyclodextrin
Catalog number: B2027400
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 mg
Molecular Weight or Concentration: 1426.2
Supplied as: Chemicals
Storage: −80°C
Keywords: 6-Perdeoxy-6-perchloro-gamma-cyclodextrin, Octakis(6-deoxy-6-chloro)-gamma-cyclodextrin, Per-6-chloro-6-deoxy-gamma-cyclodextrin
References:
1. Loftsson, T., & Duchêne, D. (2007). Cyclodextrins and their pharmaceutical applications. International Journal of Pharmaceutics, 329(1-2), 1-11.
2. Szejtli, J. (1998). Introduction and general overview of cyclodextrin chemistry. Chemical Reviews, 98(5), 1743-1754.
3. Davis, M. E., & Brewster, M. E. (2004). Cyclodextrin-based pharmaceutics: past, present and future. Nature Reviews Drug Discovery, 3(12), 1023-1035.
4. Stella, V. J., & He, Q. (2008). Cyclodextrins. Toxicologic Pathology, 36(1), 30-42.
5. Vyas, A., Saraf, S., & Saraf, S. (2008). Cyclodextrin based novel drug delivery systems. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 62(1), 23-42.
6. Del Valle, E. M. (2004). Cyclodextrins and their uses: a review. Process Biochemistry, 39(9), 1033-1046.
7. Szente, L., & Szejtli, J. (2004). Highly soluble cyclodextrin derivatives: chemistry, properties, and trends in development. Advanced Drug Delivery Reviews, 56(9), 1229-1249.
8. Kurkov, S. V., & Loftsson, T. (2013). Cyclodextrins. International Journal of Pharmaceutics, 453(1), 167-180.
9. Jansook, P., Ogawa, N., & Loftsson, T. (2018). Cyclodextrins: structure, physicochemical properties and pharmaceutical applications. International Journal of Pharmaceutics, 535(1-2), 272-284.
10. Tian, B. R., Liu, Y., & Zhang, H. Y. (2020). Randomly methylated cyclodextrins as versatile solubilizers and carriers in drug delivery. Carbohydrate Polymers, 240, 116285.
Heptakis(6-deoxy-6-chloro)-gamma-cyclodextrin
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Additional Information
| Weight | 0.15 oz |
|---|---|
| Dimensions | 2 × 0.5 × 0.5 in |
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