Heptakis(6-deoxy-6-(2-carboxyethyl)thio)-beta-cyclodextrin partly Sodiium Salt

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Heptakis(6-deoxy-6-(2-carboxyethyl)thio)-beta-cyclodextrin partly Sodiium Salt
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Heptakis(6-deoxy-6-(2-carboxyethyl)thio)-beta-cyclodextrin partly Sodiium Salt

Original price was: $1,795.00.Current price is: $895.00.

Catalog Number: B2027395 (100 mg)
Heptakis(6-deoxy-6-(2-carboxyethyl)thio)-beta-cyclodextrin partly sodium salt is a modified cyclic oligosaccharide featuring carboxyethylthio functional groups attached to the primary rim of seven glucopyranose units. These negatively charged carboxylate extensions enhance aqueous solubility and enable the formation of host-guest inclusion complexes with complementary lipophilic molecules. Supplied in a partially neutralized salt form to maintain chemical stability, it is utilized as a specialized macrocyclic host in solubilization research. Custom bulk amounts of this product are available upon request.

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Product Description

5/5 - (1 vote)

Heptakis(6-deoxy-6-(2-carboxyethyl)thio)-beta-cyclodextrin partly Sodiium Salt
Catalog number: B2027395
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 mg
Molecular Weight or Concentration: NA
Supplied as: Chemicals
Storage: −80°C
Keywords: Heptakis(6-deoxy-6-(2-carboxyethyl)thio)-β-cyclodextrin sodium salt, Sugammadex Impurity B, Sugammadex β-cyclodextrin analogue

References:
1. Loftsson, T., & Duchêne, D. (2007). Cyclodextrins and their pharmaceutical applications. International Journal of Pharmaceutics, 329(1-2), 1-11.
2. Szejtli, J. (1998). Introduction and general overview of cyclodextrin chemistry. Chemical Reviews, 98(5), 1743-1754.
3. Davis, M. E., & Brewster, M. E. (2004). Cyclodextrin-based pharmaceutics: past, present and future. Nature Reviews Drug Discovery, 3(12), 1023-1035.
4. Stella, V. J., & He, Q. (2008). Cyclodextrins. Toxicologic Pathology, 36(1), 30-42.
5. Vyas, A., Saraf, S., & Saraf, S. (2008). Cyclodextrin based novel drug delivery systems. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 62(1), 23-42.
6. Del Valle, E. M. (2004). Cyclodextrins and their uses: a review. Process Biochemistry, 39(9), 1033-1046.
7. Szente, L., & Szejtli, J. (2004). Highly soluble cyclodextrin derivatives: chemistry, properties, and trends in development. Advanced Drug Delivery Reviews, 56(9), 1229-1249.
8. Kurkov, S. V., & Loftsson, T. (2013). Cyclodextrins. International Journal of Pharmaceutics, 453(1), 167-180.
9. Jansook, P., Ogawa, N., & Loftsson, T. (2018). Cyclodextrins: structure, physicochemical properties and pharmaceutical applications. International Journal of Pharmaceutics, 535(1-2), 272-284.
10. Tian, B. R., Liu, Y., & Zhang, H. Y. (2020). Randomly methylated cyclodextrins as versatile solubilizers and carriers in drug delivery. Carbohydrate Polymers, 240, 116285.
Heptakis(6-deoxy-6-(2-carboxyethyl)thio)-beta-cyclodextrin partly Sodiium Salt

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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