HDAC Assay Buffer 5X (Biotechnology Grade)
$195.00
Catalog Number: B2010129 (10 mL)
HDAC Assay Buffer 5X is a high quality research product used as optimized buffer for Histone Deacetylase Assays (HDAC). Custom bulk orders of this product are available upon request.
In stock
Description
HDAC Assay Buffer 5X
Catalog number: B2010129
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 mL
pH: 8
Supplied as: 5X Concentrate (Dilute 1:5 before use)
Appearance: Clear solution
Applications: optimized buffer for Histone Deacetylase Assays (HDAC).
Storage: −20°C
Keywords: HDAC buffer, hdac assay buffer, hdac activity assay buffer
Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.
References:
1: Yoon S, Eom GH. HDAC and HDAC Inhibitor: From Cancer to Cardiovascular
Diseases. Chonnam Med J. 2016 Jan;52(1):1-11.
2: Hull EE, Montgomery MR, Leyva KJ. HDAC Inhibitors as Epigenetic Regulators of
the Immune System: Impacts on Cancer Therapy and Inflammatory Diseases. Biomed
Res Int. 2016;2016:8797206.
3: Booth L, Roberts JL, Poklepovic A, Kirkwood J, Dent P. HDAC inhibitors
enhance the immunotherapy response of melanoma cells. Oncotarget. 2017 May
17;8(47):83155-83170.
4: Schobert R, Biersack B. Multimodal HDAC Inhibitors with Improved Anticancer
Activity. Curr Cancer Drug Targets. 2018;18(1):39-56.
5: Lyu X, Hu M, Peng J, Zhang X, Sanders YY. HDAC inhibitors as antifibrotic
drugs in cardiac and pulmonary fibrosis. Ther Adv Chronic Dis. 2019 Jul
18;10:2040622319862697.
6: Lu H, Bai L, Zhou Y, Lu Y, Jiang Z, Shi J. Recent Study of Dual HDAC/PARP
Inhibitor for the Treatment of Tumor. Curr Top Med Chem. 2019;19(12):1041-1050.
7: Hesham HM, Lasheen DS, Abouzid KAM. Chimeric HDAC inhibitors: Comprehensive
review on the HDAC-based strategies developed to combat cancer. Med Res Rev.
2018 Sep;38(6):2058-2109.
8: Li Y, Wang F, Chen X, Wang J, Zhao Y, Li Y, He B. Zinc-dependent Deacetylase
(HDAC) Inhibitors with Different Zinc Binding Groups. Curr Top Med Chem.
2019;19(3):223-241.
9: Kim T, Song S, Park Y, Kang S, Seo H. HDAC Inhibition by Valproic Acid
Induces Neuroprotection and Improvement of PD-like Behaviors in LRRK2 R1441G
Transgenic Mice. Exp Neurobiol. 2019 Aug 31;28(4):504-515.
10: Amin SA, Adhikari N, Jha T. Is dual inhibition of metalloenzymes HDAC-8 and
MMP-2 a potential pharmacological target to combat hematological malignancies?
Pharmacol Res. 2017 Aug;122:8-19.
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