HDAC Assay Buffer 5X (Biotechnology Grade)


Catalog Number: B2010129 (10 mL)
HDAC Assay Buffer 5X is a high quality research product used as optimized buffer for Histone Deacetylase Assays (HDAC). Custom bulk orders of this product are available upon request.

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HDAC Assay Buffer 5X
Catalog number: B2010129
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 mL
pH: 8
Supplied as: 5X Concentrate (Dilute 1:5 before use)
Appearance: Clear solution
Applications: optimized buffer for Histone Deacetylase Assays (HDAC).
Storage: −20°C
Keywords: HDAC buffer, hdac assay buffer, hdac activity assay buffer
Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.

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2: Hull EE, Montgomery MR, Leyva KJ. HDAC Inhibitors as Epigenetic Regulators of
the Immune System: Impacts on Cancer Therapy and Inflammatory Diseases. Biomed
Res Int. 2016;2016:8797206.

3: Booth L, Roberts JL, Poklepovic A, Kirkwood J, Dent P. HDAC inhibitors
enhance the immunotherapy response of melanoma cells. Oncotarget. 2017 May

4: Schobert R, Biersack B. Multimodal HDAC Inhibitors with Improved Anticancer
Activity. Curr Cancer Drug Targets. 2018;18(1):39-56.

5: Lyu X, Hu M, Peng J, Zhang X, Sanders YY. HDAC inhibitors as antifibrotic
drugs in cardiac and pulmonary fibrosis. Ther Adv Chronic Dis. 2019 Jul

6: Lu H, Bai L, Zhou Y, Lu Y, Jiang Z, Shi J. Recent Study of Dual HDAC/PARP
Inhibitor for the Treatment of Tumor. Curr Top Med Chem. 2019;19(12):1041-1050.

7: Hesham HM, Lasheen DS, Abouzid KAM. Chimeric HDAC inhibitors: Comprehensive
review on the HDAC-based strategies developed to combat cancer. Med Res Rev.
2018 Sep;38(6):2058-2109.

8: Li Y, Wang F, Chen X, Wang J, Zhao Y, Li Y, He B. Zinc-dependent Deacetylase
(HDAC) Inhibitors with Different Zinc Binding Groups. Curr Top Med Chem.

9: Kim T, Song S, Park Y, Kang S, Seo H. HDAC Inhibition by Valproic Acid
Induces Neuroprotection and Improvement of PD-like Behaviors in LRRK2 R1441G
Transgenic Mice. Exp Neurobiol. 2019 Aug 31;28(4):504-515.

10: Amin SA, Adhikari N, Jha T. Is dual inhibition of metalloenzymes HDAC-8 and
MMP-2 a potential pharmacological target to combat hematological malignancies?
Pharmacol Res. 2017 Aug;122:8-19.

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