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Guanidine Thiocyanate

Original price was: $1,395.00.Current price is: $695.00.

Catalog Number: B2016330 (25 g)
Guanidine Thiocyanate is a high quality strong chaotropic agent that disrupts hydrogen bonding and denatures proteins, making it useful for extracting nucleic acids such as DNA and RNA from biological samples. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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Product Description

Guanidine Thiocyanate
Catalog number: B2016330
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 25 g
Molecular Weight or Concentration: 118.16
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: RT
Keywords: guanidine hydrothiocyanate / guanidine monothiocyanate / guanidinium rhodanide / guanidinium thiocyanate / guanidium thiocyanate / thiocyanic acid, compd. with guanidine (1:1) / USAF EK-705
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Chomczynski P, Sacchi N. The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twenty-something years on Nat Protoc. 2006;1(2):581-5.
2: Sun X, Wang M, Guo L, Shu C, Zhang J, Geng L. Guanidine thiocyanate solution facilitates sample collection for plant rhizosphere microbiome analysis PeerJ. 2019 Feb 19;7:e6440.
3: Pei Y, Mamtimin T, Ji J, Khan A, Kakade A, Zhou T, Yu Z, Zain H, Yang W, Ling Z, Zhang W, Zhang Y, Li X. The guanidine thiocyanate-high EDTA method for total microbial RNA extraction from severely heavy metal-contaminated soils Microb Biotechnol. 2021 Mar;14(2):465-478.
4: Honeywood MJ, Jeffries-Miles S, Wong K, Harrington C, Burns CC, Oberste MS, Bowen MD, Vega E. Use of guanidine_thiocyanate-based nucleic acid extraction buffers to inactivate poliovirus in potentially infectious materials J Virol Methods. 2021 Nov;297:114262.
5: Stepanenko OV, Stepanenko OV, Kuznetsova IM, Shcherbakova DM, Verkhusha VV, Turoverov KK. Distinct effects of guanidine thiocyanate on the structure of superfolder GFP PLoS One. 2012;7(11):e48809.
6: Rolfs F, de Goeij-de Haas RR, Knol JC, Piersma SR, Jimenez CR. Phosphoproteomics After Guanidinium Thiocyanate Extraction of Tissue Biopsies Methods Mol Biol. 2023;2718:285-302.
7: Baek YH, Park MY, Lim HJ, Jung HS, Yang JH, Sohn YH, Lee SH, Park JE, Yang YJ. Evaluation of Alternative Transport Media for RT-qPCR-Based SARS-CoV-2 Testing Int J Anal Chem. 2022 Aug 10;2022:5020255.
8: Drygin YF, Butenko KO, Gasanova TV. Environmentally friendly method of RNA isolation Anal Biochem. 2021 May 1;620:114113.
9: Emadi S, Behzadi M. A comparative study on the aggregating effects of guanidine thiocyanate, guanidine hydrochloride and urea on lysozyme aggregation Biochem Biophys Res Commun. 2014 Aug 8;450(4):1339-44.
10: Nishimoto Y, Mizutani S, Nakajima T, Hosoda F, Watanabe H, Saito Y, Shibata T, Yachida S, Yamada T. High stability of faecal microbiome composition in guanidine thiocyanate solution at room temperature and robustness during colonoscopy Gut. 2016 Sep;65(9):1574-5.

Products Related to Guanidine Thiocyanate can be found at Chemicals

Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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