Name: Glutamine Synthetase
Brand: Molecular Depot
SKU: B2020189
Price: 895 USD
Availability: InStock
Rating: 5 (2 reviews)

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Glutamine Synthetase

Original price was: $1,795.00.Current price is: $895.00.

Catalog Number: B2020189 (1 kU)
Glutamine synthetase is a key enzyme in nitrogen metabolism, catalyzing the synthesis of glutamine from glutamate and ammonia using ATP. It plays a vital role in detoxifying ammonia, producing glutamine for protein synthesis, and maintaining nitrogen balance in high turnover tissues. The enzyme is regulated by various factors, including allosteric effectors. This product has been used as a molecular tool for various biochemical applications. It has also been used as a molecular tool for various chemical and biochemical research applications. Custom bulk amounts of this product are available upon request.

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SKU: B2020189 Categories: Cell Biology, Enzymes Tag: MD 1000

Product Description

5/5 - (2 votes)

Glutamine Synthetase
Catalog number: B2020189
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 kU
Molecular Weight or Concentration: 900 kDa
Supplied as: Lyophilized
Applications: a molecular tool for various biochemical applications
Storage: -20C
Keywords: GST, L-Glutamate : ammonia ligase (ADP-forming)
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Eelen G, Dubois C, Cantelmo AR, Goveia J, Brüning U, DeRan M, Jarugumilli G, van Rijssel J, Saladino G, Comitani F, Zecchin A, Rocha S, Chen R, Huang H, Vandekeere S, Kalucka J, Lange C, Morales-Rodriguez F, Cruys B, Treps L, Ramer L, Vinckier S, Brepoels K, Wyns S, Souffreau J, Schoonjans L, Lamers WH, Wu Y, Haustraete J, Hofkens J, Liekens S, Cubbon R, Ghesquière B, Dewerchin M, Gervasio FL, Li X, van Buul JD, Wu X, Carmeliet P. Role of glutamine synthetase in angiogenesis beyond glutamine synthesis Nature. 2018 Sep;561(7721):63-69.
2: Eid T, Lee TW, Patrylo P, Zaveri HP. Astrocytes and Glutamine Synthetase in Epileptogenesis J Neurosci Res. 2019 Nov;97(11):1345-1362.
3: Moreira E, Coimbra S, Melo P. Glutamine synthetase: an unlikely case of functional redundancy in Arabidopsis thaliana Plant Biol (Stuttg). 2022 Aug;24(5):713-720.
4: Vitali T, Vanoni MA, Bellosta P. Quantitation of Glutamine Synthetase 1 Activity in Drosophila melanogaster Methods Mol Biol. 2023;2675:237-260.
5: Wang S, Lin R, Tumukunde E, Zeng W, Bao Q, Wang S, Wang Y. Glutamine Synthetase Contributes to the Regulation of Growth, Conidiation, Sclerotia Development, and Resistance to Oxidative Stress in the Fungus Aspergillus flavus Toxins (Basel). 2022 Nov 23;14(12):822.
6: Nguyen ED, Ding CC, Umetsu SE, Ferrell LD, Wen KW. Glutamine synthetase staining patterns in cirrhosis Hum Pathol. 2024 Nov;153:105655.
7: Betti M, García-Calderón M, Pérez-Delgado CM, Credali A, Estivill G, Galván F, Vega JM, Márquez AJ. Glutamine synthetase in legumes: recent advances in enzyme structure and functional genomics Int J Mol Sci. 2012;13(7):7994-8024.
8: Gebhardt R, Williams GM. Glutamine synthetase and hepatocarcinogenesis Carcinogenesis. 1995 Aug;16(8):1673-81.
9: Cho SG, Song M, Chuon K, Shim JG, Meas S, Jung KH. Heliorhodopsin binds and regulates glutamine synthetase activity PLoS Biol. 2022 Oct 3;20(10):e3001817.
https://pubmed.ncbi.nlm.nih.gov/33882633

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