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Factor X Depleted Human Plasma

$495.00

Catalog Number: B2012557 (5 mL)
Factor X Depleted Human Plasma is a high quality human plasma that has been immuno-depleted of Factor X. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2012557 Categories: , Tag:

Description

Factor X Depleted Human Plasma
Catalog number: B2012557
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mL
Molecular Weight or Concentration: N/A
Supplied as: Plasma
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: FX Deficient plasma
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Shapiro A. Plasma-derived human factor X concentrate for on-demand and perioperative treatment in factor X-deficient patients: pharmacology, pharmacokinetics, efficacy, and safety Expert Opin Drug Metab Toxicol. 2017 Jan;13(1):97-104.
2: Østergaard H, Lund J, Greisen PJ, Kjellev S, Henriksen A, Lorenzen N, Johansson E, Røder G, Rasch MG, Johnsen LB, Egebjerg T, Lund S, Rahbek-Nielsen H, Gandhi PS, Lamberth K, Loftager M, Andersen LM, Bonde AC, Stavenuiter F, Madsen DE, Li X, Holm TL, Ley CD, Thygesen P, Zhu H, Zhou R, Thorn K, Yang Z, Hermit MB, Bjelke JR, Hansen BG, Hilden I. A factor VIIIa-mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice Blood. 2021 Oct 7;138(14):1258-1268.
3: Muczynski V, Aymé G, Regnault V, Vasse M, Borgel D, Legendre P, Bazaa A, Harel A, Loubière C, Lenting PJ, Denis CV, Christophe OD. Complex formation with pentraxin-2 regulates factor X plasma levels and macrophage interactions Blood. 2017 Apr 27;129(17):2443-2454.
4: Menegatti M, Peyvandi F. Factor X deficiency Semin Thromb Hemost. 2009 Jun;35(4):407-15.
5: Chen Y, Qiao J, Tan W, Lu Y, Qin S, Zhang J, Li S, Bu H, Cheng J. Characterization of porcine factor VII, X and comparison with human factor VII, X Blood Cells Mol Dis. 2009 Jul-Aug;43(1):111-8.
6: Minami H, Nogami K, Yada K, Ogiwara K, Furukawa S, Soeda T, Kitazawa T, Shima M. Emicizumab, the bispecific antibody to factors IX/IXa and X/Xa, potentiates coagulation function in factor XI-deficient plasma in vitro J Thromb Haemost. 2019 Jan;17(1):126-137.
7: Hack K, Renzi F, Hess E, Lauber F, Douxfils J, Dogné JM, Cornelis GR. Inactivation of human coagulation factor X by a protease of the pathogen Capnocytophaga canimorsus J Thromb Haemost. 2017 Mar;15(3):487-499.
8: Louvain-Quintard VB, Bianchini EP, Calmel-Tareau C, Tagzirt M, Le Bonniec BF. Thrombin-activable factor X re-establishes an intrinsic amplification in tenase-deficient plasmas J Biol Chem. 2005 Dec 16;280(50):41352-9.
9: Richter G, Schwarz HP, Dorner F, Turecek PL. Activation and inactivation of human factor X by proteases derived from Ficus carica Br J Haematol. 2002 Dec;119(4):1042-51.
10: Austin SK, Brindley C, Kavakli K, Norton M, Shapiro A; FX Investigators Group. Pharmacokinetics of a high-purity plasma-derived factor X concentrate in subjects with moderate or severe hereditary factor X deficiency Haemophilia. 2016 May;22(3):426-32.

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