Digitonin (Highly Pure)

Product Description

Digitonin (Highly Pure)
Catalog number: B2017781
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 mg
Molecular Weight or Concentration: 1,229.31 g/mol
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: RT
Keywords: Digitin
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Fan HY, Heerklotz H. Digitonin does not flip across cholesterol-poor membranes J Colloid Interface Sci. 2017 Oct 15;504:283-293.
2: Cogliati S, Herranz F, Ruiz-Cabello J, Enríquez JA. Digitonin concentration is determinant for mitochondrial supercomplexes analysis by BlueNative page Biochim Biophys Acta Bioenerg. 2021 Jan 1;1862(1):148332.
3: Wojciechowski K, Orczyk M, Gutberlet T, Brezesinski G, Geue T, Fontaine P. On the Interaction between Digitonin and Cholesterol in Langmuir Monolayers Langmuir. 2016 Sep 6;32(35):9064-73.
4: Brooker G, Fleming JW, Ross EM. Radioimmunoassay of digitonin Biochim Biophys Acta. 1982 Feb 8;685(1):39-43.
5: Orczyk M, Wojciechowski K, Brezesinski G. Disordering Effects of Digitonin on Phospholipid Monolayers Langmuir. 2017 Apr 18;33(15):3871-3881.
6: Geelen MJ. The use of digitonin-permeabilized mammalian cells for measuring enzyme activities in the course of studies on lipid metabolism Anal Biochem. 2005 Dec 1;347(1):1-9.
7: Adam SA. Nuclear Protein Transport in Digitonin Permeabilized Cells Methods Mol Biol. 2016;1411:479-87.
8: Nishikawa M, Nojima S, Akiyama T, Sankawa U, Inoue K. Interaction of digitonin and its analogs with membrane cholesterol J Biochem. 1984 Oct;96(4):1231-9.
9: Kose S, Funakoshi T, Imamoto N. Reconstitution of nucleocytoplasmic transport using digitonin-permeabilized cells Methods Mol Biol. 2015;1262:291-303.
10: Graça AT, Hall M, Persson K, Schröder WP. High-resolution model of Arabidopsis Photosystem II reveals the structural consequences of digitonin-extraction Sci Rep. 2021 Jul 30;11(1):15534.

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