D-(-)-Luciferin (Highly Pure)


Catalog Number: B2012169 (5 mg)
D-(-)-Luciferin (Highly Pure) is a high quality D-(-)-Luciferin (>98.0% by HPLC). This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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D-(-)-Luciferin (Highly Pure)
Catalog number: B2012169
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 280.32 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: (S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic Acid
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Takakura H. Molecular Design of d-Luciferin-Based Bioluminescence and 1,2-Dioxetane-Based Chemiluminescence Substrates for Altered Output Wavelength and Detecting Various Molecules Molecules. 2021 Mar 15;26(6):1618.
2: Adams ST Jr, Miller SC. Beyond D-luciferin: expanding the scope of bioluminescence imaging in vivo Curr Opin Chem Biol. 2014 Aug;21:112-20.
3: Ma D, Wang H, Ugo T, Mustafa D, Zhou W, Cali JJ. Luminogenic D-Luciferin Derivatives as OATP1B1 and 1B3 Substrates in No-wash Assays Photochem Photobiol. 2021 Nov;97(6):1407-1416.
4: Smale ST. Luciferase assay Cold Spring Harb Protoc. 2010 May;2010(5):pdb.prot5421.
5: Kovács AK, Hegyes P, Szebeni GJ, Nagy LI, Puskás LG, Tóth GK. Synthesis of N-peptide-6-amino-D-luciferin Conjugates Front Chem. 2018 Apr 19;6:120.
6: Xia Y, Pang H. Glucuronidation of D-Luciferin In Vitro: Isoform Selectivity and Kinetics Characterization Eur J Drug Metab Pharmacokinet. 2019 Aug;44(4):549-556.
7: Nakajima K, Hamada K, Ito R, Yoshida Y, Sutherland K, Ishikawa M, Ozaki M, Shirato H, Hamada T. Stability of d-luciferin for bioluminescence to detect gene expression in freely moving mice for long durations Luminescence. 2021 Feb;36(1):94-98.
8: Usukura J, Hiyama M, Kurata M, Hazama Y, Qiu XP, Winnik FM, Akiyama H, Koga N. Theoretical Study of the Wavelength Selection for the Photocleavage of Coumarin-caged D-luciferin Photochem Photobiol. 2020 Jul;96(4):805-814.
9: Kurata M, Hiyama M, Narimatsu T, Hazama Y, Ito T, Hayamizu Y, Qiu X, Winnik FM, Akiyama H. Synthesis and quantitative characterization of coumarin-caged D-luciferin J Photochem Photobiol B. 2018 Dec;189:81-86.
10: Maeda J, Kato DI, Okuda M, Takeo M, Negoro S, Arima K, Ito Y, Niwa K. Biosynthesis-inspired deracemizative production of d-luciferin by combining luciferase and thioesterase Biochim Biophys Acta Gen Subj. 2017 Aug;1861(8):2112-2118.

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